Quantile rank maps: A new tool for understanding individual brain development
文献类型:期刊论文
作者 | Chen, Huaihou1; Kelly, Clare2; Castellanos, F. Xavier2,3; He, Ye4,5,6,7; Zuo, Xi-Nian5,6,7![]() |
刊名 | NEUROIMAGE
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出版日期 | 2015-05-01 |
卷号 | 111期号:1页码:454-463 |
通讯作者邮箱 | phil.reiss@nyumc.org |
关键词 | Box-Cox transformation Generalized additive models for location scale and shape Quantile rank map MRI Resting-state fMRI Penalized B-splines |
ISSN号 | 1053-8119 |
产权排序 | 4 |
通讯作者 | Philip T. Reiss |
合作状况 | 国际 |
中文摘要 | We propose a novel method for neurodevelopmental brain mapping that displays how an individual’s values for a quantity of interest compare with age-specific norms. By estimating smoothly age-varying distributions at a set of brain regions of interest, we derive age-dependent region-wise quantile ranks for a given individual, which can be presented in the form of a brain map. Such quantile rank maps could potentially be used for clinical screening. Bootstrap-based confidence intervals are proposed for the quantile rank estimates. We also propose a recalibrated Kolmogorov-Smirnov test for detecting group differences in the age-varying distribution. This test is shown to be more robust to model misspecification than a linear regression-based t-test. The proposed methods are applied to brain imaging data from the Nathan Kline Institute Rockland Sample and from the Autism Brain Imaging Data Exchange (ABIDE) sample. |
英文摘要 | We propose a novel method for neurodevelopmental brain mapping that displays how an individual's values for a quantity of interest compare with age-specific norms. By estimating smoothly age-varying distributions at a set of brain regions of interest, we derive age-dependent region-wise quantile ranks for a given individual, which can be presented in the form of a brain map. Such quantile rank maps could potentially be used for clinical screening. Bootstrap-based confidence intervals are proposed for the quantile rank estimates. We also propose a recalibrated Kolmogorov-Smirnov test for detecting group differences in the age-varying distribution. This test is shown to be more robust to model misspecification than a linear regression-based test. The proposed methods are applied to brain imaging data from the Nathan Kline Institute Rockland Sample and from the Autism Brain Imaging Data Exchange (ABIDE) sample. (C) 2015 Elsevier Inc. All rights reserved. |
学科主题 | 认知神经科学 |
收录类别 | SCI |
资助信息 | National Institutes of Health; Chinese Academy of Sciences; National Natural Science Foundation |
原文出处 | http://www.sciencedirect.com/science/article/pii/S1053811915000130 |
语种 | 英语 |
WOS记录号 | WOS:000352224100040 |
公开日期 | 2015-01-23 |
源URL | [http://ir.psych.ac.cn/handle/311026/10190] ![]() |
专题 | 心理研究所_认知与发展心理学研究室 |
作者单位 | 1.Univ Florida, Coll Med, Coll Publ Hlth & Hlth Profess, Dept Biostat, Gainesville, FL USA 2.NYU, Sch Med, Dept Child & Adolescent Psychiat, New York, NY 10016 USA 3.Nathan S Kline Inst Psychiat Res, Orangeburg, NY 10962 USA 4.Univ Chinese Acad Sci, Beijing, Peoples R China 5.Chinese Acad Sci, Key Lab Behav Sci, Beijing 100101, Peoples R China 6.Chinese Acad Sci, Inst Psychol, Magnet Resonance Imaging Res Ctr, Beijing 100101, Peoples R China 7.Chinese Acad Sci, Inst Psychol, Lab Funct Connectome & Dev, Beijing 100101, Peoples R China 8.NYU, Sch Med, Dept Populat Hlth, New York, NY USA |
推荐引用方式 GB/T 7714 | Chen, Huaihou,Kelly, Clare,Castellanos, F. Xavier,et al. Quantile rank maps: A new tool for understanding individual brain development[J]. NEUROIMAGE,2015,111(1):454-463. |
APA | Chen, Huaihou,Kelly, Clare,Castellanos, F. Xavier,He, Ye,Zuo, Xi-Nian,&Reiss, Philip T..(2015).Quantile rank maps: A new tool for understanding individual brain development.NEUROIMAGE,111(1),454-463. |
MLA | Chen, Huaihou,et al."Quantile rank maps: A new tool for understanding individual brain development".NEUROIMAGE 111.1(2015):454-463. |
入库方式: OAI收割
来源:心理研究所
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