Elevated amygdala activity during reappraisal anticipation predicts anxiety in avoidant personality disorder
文献类型：期刊论文
| 作者 | Liu X(刘勋)
|
| 刊名 | JOURNAL OF AFFECTIVE DISORDERS
 |
| 出版日期 | 2015 |
| 卷号 | 172期号:2页码:1-7 |
| 通讯作者邮箱 | HWarrenK@nyc.rr.com |
| 关键词 | Avoidant personality disorder Reappraisal Anticipation Anxiety FMRI Amygdala |
| 产权排序 | 3 |
| 通讯作者 | Harold W. Koenigsberg |
| 合作状况 | 国际 |
| 中文摘要 | Background Avoidant personality disorder is characterized by pervasive anxiety, fear of criticism, disapproval, and rejection, particularly in anticipation of exposure to social situations. An important but underexplored question concerns whether anxiety in avoidant patients is associated with an impaired ability to engage emotion regulatory strategies in anticipation of and during appraisal of negative social stimuli. Methods We examined the use of an adaptive emotion regulation strategy, cognitive reappraisal, in avoidant patients. In addition to assessing individual differences in state and trait anxiety levels, self-reported affect as well as measures of neural activity were compared between 17 avoidant patients and 21 healthy control participants both in anticipation of and during performance of a reappraisal task. Results Avoidant patients showed greater state and trait-related anxiety relative to healthy participants. In addition, relative to healthy participants, avoidant patients showed pronounced amygdala hyper-reactivity during reappraisal anticipation, and this hyper-reactivity effect was positively associated with increasing self-reported anxiety levels. Limitations Our finding of exaggerated amygdala activity during reappraisal anticipation could reflect anxiety about the impending need to reappraise, anxiety about the certainty of an upcoming negative image, or anxiety relating to anticipated scrutiny of task responses by the experimenters. While we believe that all of these possibilities are consistent with the phenomenology of avoidant personality disorder, future research may clarify this ambiguity. Conclusions These results suggest that amygdala reactivity in anticipation of receiving negative social information may represent a key component of the neural mechanisms underlying the heightened anxiety present in avoidant patients. |
| 收录类别 | SCI |
| 原文出处 | http://www.sciencedirect.com/science/article/pii/S0165032714005710 |
| 公开日期 | 2015-01-30 |
| 源URL | [http://ir.psych.ac.cn/handle/311026/10193]  |
| 专题 | 心理研究所_认知与发展心理学研究室 |
| 推荐引用方式 GB/T 7714 | Liu X. Elevated amygdala activity during reappraisal anticipation predicts anxiety in avoidant personality disorder[J]. JOURNAL OF AFFECTIVE DISORDERS,2015,172(2):1-7. |
| APA | Liu X.(2015).Elevated amygdala activity during reappraisal anticipation predicts anxiety in avoidant personality disorder.JOURNAL OF AFFECTIVE DISORDERS,172(2),1-7. |
| MLA | Liu X."Elevated amygdala activity during reappraisal anticipation predicts anxiety in avoidant personality disorder".JOURNAL OF AFFECTIVE DISORDERS 172.2(2015):1-7. |
入库方式： OAI收割
来源：心理研究所
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