Heterodimeric ent-Kauranoids from Isodon tenuifolius
文献类型：期刊论文
| 作者 | Yang, Jian-Hong1,2; Wang, Wei-Guang1; Du, Xue1; He, Fei1; Zhang, Hai-Bo1; Li, Xiao-Nian1; Li, Yan1 ; Pu, Jian-Xin1; Sun, Han-Dong1
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| 刊名 | JOURNAL OF NATURAL PRODUCTS
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| 出版日期 | 2014-11-01 |
| 卷号 | 77期号:11页码:2444-2453 |
| 关键词 | IMMUNOSUPPRESSIVE POLYKETIDES 5-AMINOLEVULINIC ACID ASSAY marine-associated fungus Daldinia eschscholzii secondary metabolites hydrolysis GC analysis X-ray diffraction analysis |
| ISSN号 | 0163-3864 |
| 产权排序 | 第一 |
| 通讯作者 | Pu,JX (reprint author),Chinese Acad Sci,State Key Lab Phytochem & Plant Resources West Ch,Kunming Inst Bot,Kunming 650201,Peoples R China. ; pujianxin@mail.kib.ac.cn |
| 英文摘要 | Thirteen new heterodimeric ent-kauranoids, bistenuifolins A-M (1-13), were isolated from the aerial parts of Isodon tenuifolius. The constituent units of compounds 1-6 were linked by a six-membered dihydropyran ring, while those of compounds 7-11 were joined by a rare single carbon-carbon bond (C-16 -> C-17'). The constituent units of 12 and 13 were linked via an unusual cyclobutane moiety. The structures of these metabolites were established via spectrometric analyses, and the absolute configurations of 1 and 4 were defined by single-crystal X-ray diffraction. Selected compounds were evaluated for their cytotoxicity against a small panel of human tumor cell lines; bistenuifolin B (2) exhibited weak inhibitory effects. |
| 学科主题 | Plant Sciences;Chemistry, Medicinal;Pharmacology & Pharmacy |
| 类目[WOS] | Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy |
| 研究领域[WOS] | Plant Sciences ; Pharmacology & Pharmacy |
| 关键词[WOS] | DITERPENOIDS ; RUBESCENS ; ABIETANE ; DIMERS |
| 收录类别 | SCI ; IC |
| 资助信息 | MFLU grant [56101020032]; Mushroom Research Foundation, Chiang Rai, Thailand; Chinese Academy of Sciences [2013T2S0030]; Humidtropics, a CGIAR Research Program; Japan Society for the Promotion of Science (JSPS) [25440199]; Distinguished Scientist Fellowship Program (DSFP), King Saud University, Saudi Arabia |
| 语种 | 英语 |
| WOS记录号 | WOS:000345472100017 |
| 公开日期 | 2015-01-20 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/18457]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources West Ch, Kunming Inst Bot, Kunming 650201, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100039, Peoples R China |
| 推荐引用方式 GB/T 7714 | Yang, Jian-Hong,Wang, Wei-Guang,Du, Xue,et al. Heterodimeric ent-Kauranoids from Isodon tenuifolius[J]. JOURNAL OF NATURAL PRODUCTS,2014,77(11):2444-2453. |
| APA | Yang, Jian-Hong.,Wang, Wei-Guang.,Du, Xue.,He, Fei.,Zhang, Hai-Bo.,...&Sun, Han-Dong.(2014).Heterodimeric ent-Kauranoids from Isodon tenuifolius.JOURNAL OF NATURAL PRODUCTS,77(11),2444-2453. |
| MLA | Yang, Jian-Hong,et al."Heterodimeric ent-Kauranoids from Isodon tenuifolius".JOURNAL OF NATURAL PRODUCTS 77.11(2014):2444-2453. |
入库方式： OAI收割
来源：昆明植物研究所
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