Exposure of fatty acids after a single oral administration of sacha inchi (Plukenetia volubilis L.) and sunflower oil in human adult subjects
文献类型：期刊论文
| 作者 | Gonzales, G. F. |
| 刊名 | Toxicology Mechanisms and Methods
 |
| 出版日期 | 2014 |
| 卷号 | 24期号:1页码:60-69 |
| ISSN号 | 1537-6516 |
| 中文摘要 | Context: Sacha inchi (Plukenetia volubilis L.) is a potential oilseed crop because it is rich in alpha-linolenic acid (ALA) (omega-3 fatty acid). Objective: To evaluate the exposure of fatty acids after a single oral administration of sacha inchi or sunflower oil in healthy volunteers. Material and methods: Plasma fatty acids concentrations were assayed by Gas Chromatography with Flame Ionization Detector in 18 adult subjects. After fasting, blood samples were obtained at 0, 0.5, 1, 2, 4, 8 and 24 h after ingestion of 10 or 15 ml of sacha inchi oil or sunflower oil. Results: The proportion ALA/linoleic acid was 1.37 in sacha inchi oil and 0.01 in sunflower oil. ALA, lauric acid, palmitic acid, linolelaidic acid, cis-8,11,14-eicosatrienoic acid, cis-13,16-docosadienoic acid and cis-4,7,10,13,16,19-docosahexaenoic acid (DHA) levels changed over time after sacha inchi oil ingestion but not with sunflower oil. The time at maximal concentration (t(max)) for ALA was 2 h after sacha inchi oil ingestion. No ALA in plasma was observed after sunflower oil consumption. The maximal concentration of ALA was 2.84 +/- 0.36 mg/ml in women and 0.94 +/- 0.57 mg/ml in men, p<0.05, whereas maximal concentration of DHA was 2.60 +/- 0.84 mg/ml in women and 1.00 +/- 0.38 mg/ml in men (p>0.05). There is a trend for higher plasma ALA levels with 15 ml sacha inchi oil. After 2 h of consumption, plasma delta triacylglycerol were reduced with sunflower oil but slightly increased with sacha inchi oil. A reduction in plasma delta triacylglycerol-rich lipoprotein cholesterol was observed with both oils. Conclusion: Consumption of sacha inchi oil increased ALA and DHA in plasma. |
| 语种 | 英语 |
| 公开日期 | 2015-02-11 |
| 源URL | [http://ir.xtbg.org.cn/handle/353005/8310]  |
| 专题 | 西双版纳热带植物园_热带植物资源可持续利用重点实验室特色文献_星油藤相关文献 |
| 推荐引用方式 GB/T 7714 | Gonzales, G. F.. Exposure of fatty acids after a single oral administration of sacha inchi (Plukenetia volubilis L.) and sunflower oil in human adult subjects[J]. Toxicology Mechanisms and Methods,2014,24(1):60-69. |
| APA | Gonzales, G. F..(2014).Exposure of fatty acids after a single oral administration of sacha inchi (Plukenetia volubilis L.) and sunflower oil in human adult subjects.Toxicology Mechanisms and Methods,24(1),60-69. |
| MLA | Gonzales, G. F.."Exposure of fatty acids after a single oral administration of sacha inchi (Plukenetia volubilis L.) and sunflower oil in human adult subjects".Toxicology Mechanisms and Methods 24.1(2014):60-69. |
入库方式： OAI收割
来源：西双版纳热带植物园
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