Hemin-functionalized WS2 nanosheets as highly active peroxidase mimetics for label-free colorimetric detection of H2O2 and glucose
文献类型：期刊论文
| 作者 | Chen Q(陈桥)1,2; Chen J(陈佳)1 ; Gao, Cunji1; Zhang ML(张明亮)1; Chen JY(陈俊英)2; Qiu HD(邱洪灯)1; Qiu HD(邱洪灯)
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| 刊名 | Analyst
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| 出版日期 | 2015 |
| 卷号 | 140期号:8页码:2857-2863 |
| ISSN号 | 0003-2654 |
| 通讯作者 | 邱洪灯 |
| 英文摘要 | Hemin-functionalized WS2 nanosheets (hemin/WS2-NSs) were first obtained by hemin assembled on the surface of few-layered WS2 nanosheets (WS2-NSs) via van der Waals interactions. Significantly, this new material possessed the advantages of both hemin and WS2 nanosheets and exhibited some unique properties. Firstly, hemin/WS2-NSs had intrinsic peroxidase-like activity, which could effectively catalyze oxidation of the substrate 3,3’,5,5’-tetramethylbenzidine (TMB) by H2O2 to produce a typical blue colored reaction. Secondly, the activity of hemin/WS2-NSs was much higher than the activity of hemin or WS2-NSs alone. The catalytic activity followed the typical Michaelis–Menten kinetics and was dependent on the temperature, pH, H2O2 concentration, as well as reaction time. Based on this finding, a new highly sensitive and selective colorimetric method for H2O2 and glucose detection was developed. This method was simple and inexpensive for glucose detection using glucose oxidase (GOx) and hemin/WS2-NSs with a linear range of 0.5 × 10−5 to 2.0 × 10−4 mol L−1 with a detection limit of 1.5 × 10−6 mol L−1. The good catalytic activity and low-cost make the hemin/WS2-NSs a useful biocatalyst for a wide range of potential applications in environmental chemistry, biotechnology and clinical diagnostics. |
| 学科主题 | 分析化学与药物化学 |
| 收录类别 | SCI |
| 资助信息 | the National Natural Science Foundation of China (no. 21405163; 21475142);the “Hundred Talents Program” of the Chinese Academy of Science;the Foundation for Sci&Tech Research Project of Gansu province (145RJYA271) |
| 语种 | 英语 |
| WOS记录号 | WOS:000352141800041 |
| 公开日期 | 2015-05-12 |
| 源URL | [http://210.77.64.217/handle/362003/7217]  |
| 专题 | 兰州化学物理研究所_中科院西北特色植物资源化学重点实验室/甘肃省天然药物重点实验室 |
| 通讯作者 | Qiu HD(邱洪灯) |
| 作者单位 | 1.Chinese Acad Sci, Key Lab Chem Northwestern Plant Resources, Key Lab Nat Med Gansu Prov, Lanzhou Inst Chem Phys, Lanzhou 730000, Peoples R China 2.Southwest Jiaotong Univ, Minist Educ, Sch Mat Sci & Engn, Key Lab Adv Technol Mat, Chengdu 610031, Peoples R China |
| 推荐引用方式 GB/T 7714 | Chen Q,Chen J,Gao, Cunji,et al. Hemin-functionalized WS2 nanosheets as highly active peroxidase mimetics for label-free colorimetric detection of H2O2 and glucose[J]. Analyst,2015,140(8):2857-2863. |
| APA | Chen Q.,Chen J.,Gao, Cunji.,Zhang ML.,Chen JY.,...&邱洪灯.(2015).Hemin-functionalized WS2 nanosheets as highly active peroxidase mimetics for label-free colorimetric detection of H2O2 and glucose.Analyst,140(8),2857-2863. |
| MLA | Chen Q,et al."Hemin-functionalized WS2 nanosheets as highly active peroxidase mimetics for label-free colorimetric detection of H2O2 and glucose".Analyst 140.8(2015):2857-2863. |
入库方式： OAI收割
来源：兰州化学物理研究所
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