Target-responsive DNA-capped nanocontainer used for fabricating universal detector and performing logic operations
文献类型：期刊论文
| 作者 | Wu, Li ; Ren, Jinsong ; Qu, Xiaogang |
| 刊名 | nucleic acids research
 |
| 出版日期 | 2014 |
| 卷号 | 42期号:21页码:e160 |
| 关键词 | MESOPOROUS SILICA NANOPARTICLES HUMAN APOLIPOPROTEIN-E CDSE/ZNS QUANTUM DOTS SINGLE-STRANDED-DNA FUNCTIONALIZED GRAPHENE SIGNAL-AMPLIFICATION GATE OPERATIONS MOLECULAR LOGIC METAL-IONS ELECTROCHEMICAL IMMUNOASSAY |
| ISSN号 | 0305-1048 |
| 通讯作者 | qu,xg |
| 中文摘要 | nucleic acids have become a powerful tool in nanotechnology because of their controllable diverse conformational transitions and adaptable higher-order nanostructure. using single-stranded dna probes as the pore-caps for various target recognition, here we present an ultrasensitive universal electrochemical detection system based on graphene and mesoporous silica, and achieve sensitivity with all of the major classes of analytes and simultaneously realize dna logic gate operations. the concept is based on the locking of the pores and preventing the signal-reporter molecules from escape by target-induced the conformational change of the tailored dna caps. the coupling of 'waking up' gatekeeper with highly specific biochemical recognition is an innovative strategy for the detection of various targets, able to compete with classical methods which need expensive instrumentation and sophisticated experimental operations. |
| 收录类别 | SCI收录期刊论文 |
| 语种 | 英语 |
| WOS记录号 | WOS:000347914600001 |
| 公开日期 | 2015-03-25 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/50662]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Wu, Li,Ren, Jinsong,Qu, Xiaogang. Target-responsive DNA-capped nanocontainer used for fabricating universal detector and performing logic operations[J]. nucleic acids research,2014,42(21):e160. |
| APA | Wu, Li,Ren, Jinsong,&Qu, Xiaogang.(2014).Target-responsive DNA-capped nanocontainer used for fabricating universal detector and performing logic operations.nucleic acids research,42(21),e160. |
| MLA | Wu, Li,et al."Target-responsive DNA-capped nanocontainer used for fabricating universal detector and performing logic operations".nucleic acids research 42.21(2014):e160. |
入库方式： OAI收割
来源：长春应用化学研究所
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