Ultra-small BaGdF5-based upconversion nanoparticles as drug carriers and multimodal imaging probes
文献类型：期刊论文
| 作者 | Yang, Dongmei ; Dai, Yunlu ; Liu, Jianhua ; Zhou,Ying ; Chen,Yinyin ; Li,Chunxia ; Ma,Pingan ; Lin,Jun |
| 刊名 | biomaterials
 |
| 出版日期 | 2014 |
| 卷号 | 35期号:6页码:2011-2023 |
| 关键词 | MESOPOROUS SILICA NANOPARTICLES LANTHANIDE-DOPED NANOPARTICLES RAY COMPUTED-TOMOGRAPHY MRI CONTRAST AGENTS MAGNETIC-RESONANCE UPCONVERTING NANOPARTICLES PHOTODYNAMIC THERAPY NAYF4 NANOCRYSTALS FACILE SYNTHESIS CANCER-THERAPY |
| ISSN号 | 0142-9612 |
| 通讯作者 | ma,pa |
| 中文摘要 | a new type of drug-delivery system (dds) was constructed, in which the anti-cancer drug doxorubicin (dox) was conjugated to the ultra-small sized (sub-10 nm) bagdf5:yb3+/tm3+ based upconversion nanoparticles (ucnps). this multifunctional dds simultaneously possesses drug delivery and optical/magnetic/x-ray computed tomography imaging capabilities. the dox can be selectively released by cleavage of hydrazone bonds in acidic environment, which shows a ph-triggered drug release behavior. the mtt assay shows these dox-conjugated ucnps exhibit obvious cytotoxic effect on hela cells. moreover, to improve the upconversion luminescence intensity, core shell structured ucnps were constructed. |
| 收录类别 | SCI收录期刊论文 |
| 语种 | 英语 |
| WOS记录号 | WOS:000331018700023 |
| 公开日期 | 2015-03-25 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/50668]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Yang, Dongmei,Dai, Yunlu,Liu, Jianhua,et al. Ultra-small BaGdF5-based upconversion nanoparticles as drug carriers and multimodal imaging probes[J]. biomaterials,2014,35(6):2011-2023. |
| APA | Yang, Dongmei.,Dai, Yunlu.,Liu, Jianhua.,Zhou,Ying.,Chen,Yinyin.,...&Lin,Jun.(2014).Ultra-small BaGdF5-based upconversion nanoparticles as drug carriers and multimodal imaging probes.biomaterials,35(6),2011-2023. |
| MLA | Yang, Dongmei,et al."Ultra-small BaGdF5-based upconversion nanoparticles as drug carriers and multimodal imaging probes".biomaterials 35.6(2014):2011-2023. |
入库方式： OAI收割
来源：长春应用化学研究所
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