Studying the mechanism of CD47-SIRP alpha interactions on red blood cells by single molecule force spectroscopy
文献类型：期刊论文
| 作者 | Pan, Yangang ; Wang, Feng ; Liu, Yanhou ; Jiang,Junguang ; Yang,Yong-Guang ; Wang,Hongda |
| 刊名 | nanoscale
 |
| 出版日期 | 2014 |
| 卷号 | 6期号:17页码:9951-9954 |
| 关键词 | INTEGRIN-ASSOCIATED PROTEIN CD47 EXPRESSION RECOGNITION BINDING MICROSCOPY STORAGE FAMILY |
| ISSN号 | 2040-3364 |
| 通讯作者 | yang,yg |
| 中文摘要 | the interaction forces and binding kinetics between sirpa and cd47 were investigated by single-molecule force spectroscopy (smfs) on both fresh and experimentally aged human red blood cells (hrbcs). we found that cd47 experienced a conformation change after oxidation, which influenced the interaction force and the position of the energy barrier between sirpa and cd47. our results are significant for understanding the mechanism of phagocytosis of red blood cells at the single molecule level. |
| 收录类别 | SCI收录期刊论文 |
| 语种 | 英语 |
| WOS记录号 | WOS:000340520500007 |
| 公开日期 | 2015-03-27 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/50714]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Pan, Yangang,Wang, Feng,Liu, Yanhou,et al. Studying the mechanism of CD47-SIRP alpha interactions on red blood cells by single molecule force spectroscopy[J]. nanoscale,2014,6(17):9951-9954. |
| APA | Pan, Yangang,Wang, Feng,Liu, Yanhou,Jiang,Junguang,Yang,Yong-Guang,&Wang,Hongda.(2014).Studying the mechanism of CD47-SIRP alpha interactions on red blood cells by single molecule force spectroscopy.nanoscale,6(17),9951-9954. |
| MLA | Pan, Yangang,et al."Studying the mechanism of CD47-SIRP alpha interactions on red blood cells by single molecule force spectroscopy".nanoscale 6.17(2014):9951-9954. |
入库方式： OAI收割
来源：长春应用化学研究所
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