Acute toxicity evaluation for quinolone antibiotics and their chlorination disinfection processes
文献类型：期刊论文
| 作者 | Li, Min ; Wei, Dongbin ; Du, Yuguo |
| 刊名 | JOURNAL OF ENVIRONMENTAL SCIENCES-CHINA
 |
| 出版日期 | 2014 |
| 卷号 | 26期号:9页码:1837-1842 |
| 关键词 | Quinolones Acute toxicity QSAR Mechanism Chlorination |
| ISSN号 | 1001-0742 |
| 中文摘要 | Acute toxicity of 21 quinolone antibiotics was monitored using photobacterium Vibrio fischeri assay. The minimum IC20 (inhibitory concentration for 20% luminescence elimination) was obtained at the least 18.86 mu mol/L for the tested quinolones. A quantitative structure-activity relationship model was established to investigate the possible mechanism for the acute toxicity. The critical physicochemical descriptors, describing sigma and pi atom electronegativity, implied that the electron transfer might occur between the quinolones and photobacterium V. fischeri. Although the quinolones exhibited limited acute toxicity to photobacterium, toxicity elevation was detected after their chlorination. Hence, chlorination disinfection treatment of quinolone-containing water should be of concerns. (C) 2014 The Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences. Published by Elsevier B.V. |
| WOS记录号 | WOS:000341739600010 |
| 公开日期 | 2015-03-24 |
| 源URL | [http://ir.rcees.ac.cn/handle/311016/9309]  |
| 专题 | 生态环境研究中心_环境化学与生态毒理学国家重点实验室 生态环境研究中心_中国科学院环境生物技术重点实验室 |
| 推荐引用方式 GB/T 7714 | Li, Min,Wei, Dongbin,Du, Yuguo. Acute toxicity evaluation for quinolone antibiotics and their chlorination disinfection processes[J]. JOURNAL OF ENVIRONMENTAL SCIENCES-CHINA,2014,26(9):1837-1842. |
| APA | Li, Min,Wei, Dongbin,&Du, Yuguo.(2014).Acute toxicity evaluation for quinolone antibiotics and their chlorination disinfection processes.JOURNAL OF ENVIRONMENTAL SCIENCES-CHINA,26(9),1837-1842. |
| MLA | Li, Min,et al."Acute toxicity evaluation for quinolone antibiotics and their chlorination disinfection processes".JOURNAL OF ENVIRONMENTAL SCIENCES-CHINA 26.9(2014):1837-1842. |
入库方式： OAI收割
来源：生态环境研究中心
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。