Stereoselectivity in bioaccumulation and excretion of epoxiconazole by mealworm beetle (Tenebrio molitor) larvae
文献类型：期刊论文
| 作者 | Wang, Huili
|
| 刊名 | ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
 |
| 出版日期 | 2014 |
| 卷号 | 107期号:1页码:71-76 |
| 关键词 | Tenebrio molitor larvae Epoxiconazole Stereoselectivity Bioaccumulation Excretion |
| ISSN号 | 0147-6513 |
| 中文摘要 | Stereoselectivity in bioaccumulation and excretion of stereoisomers of epoxiconazole by mealworm beetle (Tenebrio molitor) larvae through dietary exposure was investigated. Liquid chromatography tandem mass spectrometry (HPLC-MS/MS) method that use a ChiralcelOD-3R[cellulosetris-Tris-(3, 5-dichlorophenyl-carbamate)] chromatography column was applied to carry out chiral separation of the stereoisomers. Wheat bran was spiked with racemic epoxiconazole at two dose levels of 20 mg/kg and 2 mg/kg (dry weight) to feed T. molitor larvae. The results showed that both the doses of epoxiconazole were taken up by Tenebrio molitor larvae rapidly at the initial stages. There was a significant trend of stereoselective bioaccumulation in the larvae with a preferential accumulation of (-)-epoxiconazole in the 20 mg/kg dose. The stereoselectivity in bioaccumulation in the 2 mg/kg dosage was not obvious compared to the 20 mg/kg group. Results of excretion indicated an active excretion is an important pathway for the larvae to eliminate epoxiconazole which was a passive transport process with non stereoselectivity. The faster elimination might be the reason for the low accumulation of epoxiconazole, as measured by bioaccumulation factor (BAF). (C) 2014 Elsevier Inc. All rights reserved. |
| WOS记录号 | WOS:000342122000010 |
| 公开日期 | 2015-03-26 |
| 源URL | [http://ir.rcees.ac.cn/handle/311016/9676]  |
| 专题 | 生态环境研究中心_中国科学院环境生物技术重点实验室 |
| 推荐引用方式 GB/T 7714 | Wang, Huili. Stereoselectivity in bioaccumulation and excretion of epoxiconazole by mealworm beetle (Tenebrio molitor) larvae[J]. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY,2014,107(1):71-76. |
| APA | Wang, Huili.(2014).Stereoselectivity in bioaccumulation and excretion of epoxiconazole by mealworm beetle (Tenebrio molitor) larvae.ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY,107(1),71-76. |
| MLA | Wang, Huili."Stereoselectivity in bioaccumulation and excretion of epoxiconazole by mealworm beetle (Tenebrio molitor) larvae".ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY 107.1(2014):71-76. |
入库方式： OAI收割
来源：生态环境研究中心
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