DNA-Gold Nanoparticle Conjugates-Based Nanoplasmonic Probe for Specific Differentiation of Cell Types
文献类型：期刊论文
| 作者 | Yang, XF ; Li, J ; Pei, H ; Zhao, Y ; Zuo, XL ; Fan, CH ; Huang, Q |
| 刊名 | ANALYTICAL CHEMISTRY
 |
| 出版日期 | 2014 |
| 卷号 | 86期号:6页码:3227—3231 |
| 关键词 | SENSOR ARRAY CANCER-CELLS PROTEIN APTAMERS NANOSTRUCTURES IDENTIFICATION RECOGNITION EVOLUTION MEDICINE SURFACES |
| ISSN号 | 0003-2700 |
| 通讯作者 | huangqing@sinap.ac.cn |
| 英文摘要 | The direct analysis of cancerous cells provides a new way for cancer detection that obviates cell lysis and other tedious steps (e.g., enrichment, purification, and amplification steps). However, the analysis of different cell types remains challenging due to the subtle differences in cell surface features. Here, we have demonstrated nanoplasmonic differentiation of cell types by using DNA-gold nanoparticle nanoconjugates (DNA-AuNPs). Our strategy relies on cross reactive receptors (a collection of DNA-AuNPs) that are employed to bind the different cells that produce fingerprint-like patterns for each type of cell. Because of the enhanced nanoplasmonic effect of AuNPs via seeded-growth, we could effectively differentiate various cell lines, e.g., 786-O, L929, Hela, and RAW264.7, with dark-field microscopy or even naked eyes. |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000333235700057 |
| 公开日期 | 2015-03-13 |
| 源URL | [http://ir.sinap.ac.cn/handle/331007/14089]  |
| 专题 | 上海应用物理研究所_中科院上海应用物理研究所2011-2017年 |
| 推荐引用方式 GB/T 7714 | Yang, XF,Li, J,Pei, H,et al. DNA-Gold Nanoparticle Conjugates-Based Nanoplasmonic Probe for Specific Differentiation of Cell Types[J]. ANALYTICAL CHEMISTRY,2014,86(6):3227—3231. |
| APA | Yang, XF.,Li, J.,Pei, H.,Zhao, Y.,Zuo, XL.,...&Huang, Q.(2014).DNA-Gold Nanoparticle Conjugates-Based Nanoplasmonic Probe for Specific Differentiation of Cell Types.ANALYTICAL CHEMISTRY,86(6),3227—3231. |
| MLA | Yang, XF,et al."DNA-Gold Nanoparticle Conjugates-Based Nanoplasmonic Probe for Specific Differentiation of Cell Types".ANALYTICAL CHEMISTRY 86.6(2014):3227—3231. |
入库方式： OAI收割
来源：上海应用物理研究所
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