Morphology Change and Detachment of Lipid Bilayers from the Mica Substrate Driven by Graphene Oxide Sheets
文献类型：期刊论文
| 作者 | Lei, HZ ; Zhou, XJ ; Wu, HX ; Song, Y ; Hu, J ; Guo, SW ; Zhang, Y |
| 刊名 | LANGMUIR
 |
| 出版日期 | 2014 |
| 卷号 | 30期号:16页码:4678—4683 |
| 关键词 | ATOMIC-FORCE MICROSCOPY SUPPORTED MEMBRANES CELLS ADSORPTION DELIVERY TRANSPARENT NANOSHEETS NANOSCALE AUTOPHAGY OXIDATION |
| ISSN号 | 0743-7463 |
| 通讯作者 | zhangyi@sinap.ac.cn |
| 英文摘要 | Understanding the interaction between graphene oxide (GO) and a lipid membrane is significant for exploring the biocompatibility and cytotoxicity of GO, which is the basis for utilizing GO in the fields of biosensors, bioimaging drug delivery, antibacterials, and so on. In this article, we monitored the dynamic process of the morphology change and detachment of lipid bilayers on mica substrates prompted by GO sheets by in situ atomic force microscope (AFM) imaging. It was found that the bare lipid bilayer dramatically expanded in height and would be unstable and detachable from the mica substrates as induced by GO. The detached lipid molecules were found to bind to the GO surface. The results also imply that GO is likely to influence the height and stability of the supported lipid bilayers (SLBs) by adsorbing metal ions such as calcium ions that were used to stabilize the bilayer structures on the mica substrate. These findings illustrate a complicated effect of GO on the SLBs and should be helpful in future applications of GO in biotechnology. |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000335297300019 |
| 公开日期 | 2015-03-13 |
| 源URL | [http://ir.sinap.ac.cn/handle/331007/14257]  |
| 专题 | 上海应用物理研究所_中科院上海应用物理研究所2011-2017年 |
| 推荐引用方式 GB/T 7714 | Lei, HZ,Zhou, XJ,Wu, HX,et al. Morphology Change and Detachment of Lipid Bilayers from the Mica Substrate Driven by Graphene Oxide Sheets[J]. LANGMUIR,2014,30(16):4678—4683. |
| APA | Lei, HZ.,Zhou, XJ.,Wu, HX.,Song, Y.,Hu, J.,...&Zhang, Y.(2014).Morphology Change and Detachment of Lipid Bilayers from the Mica Substrate Driven by Graphene Oxide Sheets.LANGMUIR,30(16),4678—4683. |
| MLA | Lei, HZ,et al."Morphology Change and Detachment of Lipid Bilayers from the Mica Substrate Driven by Graphene Oxide Sheets".LANGMUIR 30.16(2014):4678—4683. |
入库方式： OAI收割
来源：上海应用物理研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。