Self-assembly of DNA-based drug delivery nanocarriers with rolling circle amplification
文献类型：期刊论文
| 作者 | Ouyang, XY ; Li, J ; Liu, HJ ; Zhao, B ; Yan, J ; He, DN ; Fan, CH ; Chao, J |
| 刊名 | METHODS
 |
| 出版日期 | 2014 |
| 卷号 | 67期号:2页码:198—204 |
| 关键词 | BACTERIAL-DNA INTRACELLULAR DELIVERY GOLD NANOPARTICLES CPG MOTIFS PLATFORM NANOSTRUCTURES TRANSPORT ORIGAMI CARRIER OLIGONUCLEOTIDE |
| ISSN号 | 1046-2023 |
| 通讯作者 | fchh@sinap.ac.cn ; chaojie@sinap.ac.cn |
| 英文摘要 | DNA nanostructures have recently emerged as a type of drug delivery nanocarriers due to their suitable sizes, well-defined structures and low-toxicity. Here, we present a protocol for the assembly of DNA nanoribbon structures with rolling circle amplification (RCA) and delivery of CpG oligonucleotide. DNA nanoribbons with different dimensions and patterns were assembled with long RCA strands and several short staples. Significantly, we demonstrated they exhibited high-efficiency cellular uptake and improved immunostimulatory activity compared with ss- or ds- DNA. (C) 2013 Elsevier Inc. All rights reserved. |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000335623900013 |
| 公开日期 | 2015-03-13 |
| 源URL | [http://ir.sinap.ac.cn/handle/331007/14381]  |
| 专题 | 上海应用物理研究所_中科院上海应用物理研究所2011-2017年 |
| 推荐引用方式 GB/T 7714 | Ouyang, XY,Li, J,Liu, HJ,et al. Self-assembly of DNA-based drug delivery nanocarriers with rolling circle amplification[J]. METHODS,2014,67(2):198—204. |
| APA | Ouyang, XY.,Li, J.,Liu, HJ.,Zhao, B.,Yan, J.,...&Chao, J.(2014).Self-assembly of DNA-based drug delivery nanocarriers with rolling circle amplification.METHODS,67(2),198—204. |
| MLA | Ouyang, XY,et al."Self-assembly of DNA-based drug delivery nanocarriers with rolling circle amplification".METHODS 67.2(2014):198—204. |
入库方式： OAI收割
来源：上海应用物理研究所
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