Tryptamine functionalized reduced graphene oxide for label-free DNA impedimetric biosensing
文献类型：期刊论文
| 作者 | Zhang, Z ; Luo, LQ ; Chen, GF ; Ding, YP ; Deng, DM ; Fan, CH |
| 刊名 | BIOSENSORS & BIOELECTRONICS
 |
| 出版日期 | 2014 |
| 卷号 | 60页码:161—166 |
| 关键词 | ELECTROCHEMICAL BIOSENSOR HYBRID MATERIALS NANOCOMPOSITES GRAPHITE SHEETS FILMS AMPLIFICATION EXFOLIATION COMPOSITES MICROSCOPY |
| ISSN号 | 0956-5663 |
| 通讯作者 | luck@shu.edu.cn |
| 英文摘要 | A novel simple protocol of synthesizing tryptamine-functionalized reduced graphene oxide (TRA-rGO) was proposed to fabricate label-free electrochemical impedance DNA biosensor. TRA was anchored to rGO with its indole ring via pi-stacking interaction. The morphology, conductivity and interaction of TRA-rGO were characterized by atomic force microscopy, high resolution transmission electron microscopy, cyclic voltammetry, electrochemical impedance spectroscopy (EIS) as well as Raman and fluorescence spectroscopy. The amino-substituted oligonucleotide probe was conjugated to TRA by cross-linker glutaraldehyde for preparing an electrochemical biosensing platform. The DNA hybridization reaction of oligonucleotide probe with target DNA was monitored by EIS. Under optimum conditions, the proposed biosensor exhibited high sensitivity and low detection limit for detecting complementary oligonucleotide. The target oligonucleotide could be quantified in a wide range of 1.0 x 10(-12)-1.0 x 10(-7) M with low detection limit of 5.2 x 10(-13) M (S/N=3). (C) 2014 Elsevier B.V. All rights reserved. |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000337863900022 |
| 公开日期 | 2015-03-13 |
| 源URL | [http://ir.sinap.ac.cn/handle/331007/14530]  |
| 专题 | 上海应用物理研究所_中科院上海应用物理研究所2011-2017年 |
| 推荐引用方式 GB/T 7714 | Zhang, Z,Luo, LQ,Chen, GF,et al. Tryptamine functionalized reduced graphene oxide for label-free DNA impedimetric biosensing[J]. BIOSENSORS & BIOELECTRONICS,2014,60:161—166. |
| APA | Zhang, Z,Luo, LQ,Chen, GF,Ding, YP,Deng, DM,&Fan, CH.(2014).Tryptamine functionalized reduced graphene oxide for label-free DNA impedimetric biosensing.BIOSENSORS & BIOELECTRONICS,60,161—166. |
| MLA | Zhang, Z,et al."Tryptamine functionalized reduced graphene oxide for label-free DNA impedimetric biosensing".BIOSENSORS & BIOELECTRONICS 60(2014):161—166. |
入库方式： OAI收割
来源：上海应用物理研究所
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