Near-infrared light-responsive supramolecular nanovalve based on mesoporous silica-coated gold nanorods
文献类型：期刊论文
| 作者 | Zhang J.; Zhang J.; Zhang J.; Jia P.
|
| 刊名 | Chemical Science
 |
| 出版日期 | 2014 |
| 卷号 | 5期号:7页码:2804-2808 |
| ISSN号 | ISBN/2041-6520 |
| 英文摘要 | We constructed a novel cancer theranostic hybrid platform, based on mesoporous silica-coated gold nanorods (AuNR@MSN) gated by sulfonatocalix[4] arene (SC[4] A) switches, for bio-friendly near-infrared (NIR) light-triggered cargo release in a remote and stepwise fashion. The advantages of supramolecular switches, mesoporous silicas, and AuNRs were combined in one drug delivery system. Mesoporous silicas coated on AuNRs guarantee a high drug payload and can be easily post-functionalized. Significantly, the plasmonic heating from the NIR light-stimulated AuNR cores can decrease the ringstalk binding affinity, leading to the dissociation of SC[4] A rings from the stalks, thus opening the nanovalves and releasing the cargos. The NIR light-responsive mechanized AuNR@MSN offers exciting prospects for non-invasive controlled drug delivery, being more effective and safer than other techniques. |
| 收录类别 | SCI ; EI |
| 语种 | 英语 |
| 源URL | [http://ir.ciomp.ac.cn/handle/181722/44185]  |
| 专题 | 长春光学精密机械与物理研究所_中科院长春光机所知识产出 |
| 推荐引用方式 GB/T 7714 | Zhang J.,Zhang J.,Zhang J.,et al. Near-infrared light-responsive supramolecular nanovalve based on mesoporous silica-coated gold nanorods[J]. Chemical Science,2014,5(7):2804-2808. |
| APA | Zhang J.,Zhang J.,Zhang J.,&Jia P..(2014).Near-infrared light-responsive supramolecular nanovalve based on mesoporous silica-coated gold nanorods.Chemical Science,5(7),2804-2808. |
| MLA | Zhang J.,et al."Near-infrared light-responsive supramolecular nanovalve based on mesoporous silica-coated gold nanorods".Chemical Science 5.7(2014):2804-2808. |
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