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A Neural Implementation of Wald's Sequential Probability Ratio Test
文献类型：期刊论文
| 作者 | Kira, Shinichiro; Yang, Tianming; Shadlen, Michael N. |
| 刊名 | NEURON
 |
| 出版日期 | 2015 |
| 卷号 | 85期号:4页码:861-873 |
| 关键词 | PERCEPTUAL DECISION-MAKING COMPETING ACCUMULATOR MODEL PARAMETRIC WORKING-MEMORY PREFRONTAL CORTEX SENSORY STIMULI VISUAL-MOTION MACAQUE MONKEY BRAIN INTEGRATION |
| 通讯作者 | Shadlen, MN (reprint author), Columbia Univ Coll Phys & Surg, Dept Neurosci, 630 W 168th St, New York, NY 10032 USA. |
| 英文摘要 | Difficult decisions often require evaluation of samples of evidence acquired sequentially. A sensible strategy is to accumulate evidence, weighted by its reliability, until sufficient support is attained. An optimal statistical approach would accumulate evidence in units of logarithms of likelihood ratios (logLR) to a desired level. Studies of perceptual decisions suggest that the brain approximates an analogous procedure, but a direct test of accumulation, in units of logLR, to a threshold in units of cumulative logLR is lacking. We trained rhesus monkeys to make decisions based on a sequence of evanescent, visual cues assigned different logLR, hence different reliability. Firing rates of neurons in the lateral intraparietal area (LIP) reflected the accumulation of logLR and reached a stereotyped level before the monkeys committed to a decision. The monkeys' choices and reaction times, including their variability, were explained by LIP activity in the context of accumulation of logLR to a threshold. |
| WOS标题词 | Neurosciences & Neurology |
| 学科主题 | Neurosciences |
| 语种 | 英语 |
| WOS记录号 | WOS:000349959900020 |
| 公开日期 | 2015-05-27 |
| 源URL | [http://ir.sibs.ac.cn/handle/331001/2662]  |
| 专题 | 上海神经科学研究所_神经所(总) |
| 推荐引用方式 GB/T 7714 | Kira, Shinichiro,Yang, Tianming,Shadlen, Michael N.. A Neural Implementation of Wald's Sequential Probability Ratio Test[J]. NEURON,2015,85(4):861-873. |
| APA | Kira, Shinichiro,Yang, Tianming,&Shadlen, Michael N..(2015).A Neural Implementation of Wald's Sequential Probability Ratio Test.NEURON,85(4),861-873. |
| MLA | Kira, Shinichiro,et al."A Neural Implementation of Wald's Sequential Probability Ratio Test".NEURON 85.4(2015):861-873. |
入库方式： OAI收割
来源：上海神经科学研究所
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