The potent antimicrobial properties of cell penetrating peptide-conjugated silver nanoparticles with excellent selectivity for Gram-positive bacteria over erythrocytes
文献类型：期刊论文
| 作者 | Liu, Lihong1; Yang, Jun2; Xie, Jianping3; Luo, Zhentao3; Jiang, Jiang4; Yang, Yi Yan5; Liu, Shaomin1 |
| 刊名 | NANOSCALE
 |
| 出版日期 | 2013 |
| 卷号 | 5期号:9页码:3834-3840 |
| ISSN号 | 2040-3364 |
| 英文摘要 | Silver nanoparticles are of great interest for use as antimicrobial agents. Studies aimed at producing potent nano-silver biocides have focused on manipulation of particle size, shape, composition and surface charge. Here, we report the cell penetrating peptide catalyzed formation of antimicrobial silver nanoparticles in N, N-dimethylformamide. The novel nano-composite demonstrated a distinctly enhanced biocidal effect toward bacteria (Gram-positive Bacillus subtilis, Gram-negative Escherichia coli) and pathogenic yeast (Candida albicans), as compared to triangular and extremely small silver nanoparticles. In addition, a satisfactory biocompatibility was verified by a haemolysis test. Our results provide a paradigm in developing strategies that can maximize the silver nanoparticle application potentials while minimizing the toxic effects. |
| WOS标题词 | Science & Technology ; Physical Sciences ; Technology |
| 类目[WOS] | Chemistry, Multidisciplinary ; Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary ; Physics, Applied |
| 研究领域[WOS] | Chemistry ; Science & Technology - Other Topics ; Materials Science ; Physics |
| 关键词[WOS] | ANTIBACTERIAL ACTIVITY ; NEGATIVE BACTERIA ; ESCHERICHIA-COLI ; IONS |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000317859400036 |
| 公开日期 | 2015-05-27 |
| 源URL | [http://ir.ipe.ac.cn/handle/122111/13346]  |
| 专题 | 过程工程研究所_研究所（批量导入） |
| 作者单位 | 1.Curtin Univ Technol, Dept Chem Engn, Perth, WA 6148, Australia 2.Chinese Acad Sci, Inst Proc Engn, Beijing 100190, Peoples R China 3.Natl Univ Singapore, Dept Chem & Biomol Engn, Singapore 117576, Singapore 4.Chinese Acad Sci, Suzhou Inst Nanotech & Nanobion, Suzhou 215123, Peoples R China 5.Inst Bioengn & Nanotechnol, Singapore 138669, Singapore |
| 推荐引用方式 GB/T 7714 | Liu, Lihong,Yang, Jun,Xie, Jianping,et al. The potent antimicrobial properties of cell penetrating peptide-conjugated silver nanoparticles with excellent selectivity for Gram-positive bacteria over erythrocytes[J]. NANOSCALE,2013,5(9):3834-3840. |
| APA | Liu, Lihong.,Yang, Jun.,Xie, Jianping.,Luo, Zhentao.,Jiang, Jiang.,...&Liu, Shaomin.(2013).The potent antimicrobial properties of cell penetrating peptide-conjugated silver nanoparticles with excellent selectivity for Gram-positive bacteria over erythrocytes.NANOSCALE,5(9),3834-3840. |
| MLA | Liu, Lihong,et al."The potent antimicrobial properties of cell penetrating peptide-conjugated silver nanoparticles with excellent selectivity for Gram-positive bacteria over erythrocytes".NANOSCALE 5.9(2013):3834-3840. |
入库方式： OAI收割
来源：过程工程研究所
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