Development of an efficient CFD-simulation method to optimize the structure parameters of an airlift sonobioreactor
文献类型：期刊论文
| 作者 | Liu, Rui; Liu, Ying; Liu, Chun-Zhao |
| 刊名 | CHEMICAL ENGINEERING RESEARCH & DESIGN
 |
| 出版日期 | 2013-02-01 |
| 卷号 | 91期号:2页码:211-220 |
| 关键词 | Computational fluid dynamics Reactor design Hydrodynamics Sonobioreactor Hairy root |
| 英文摘要 | A two-dimensional CFD model was developed for optimizing the structure design of an airlift sonobioreactor for hairy root culture, and a height to diameter ratio of 4 was found suitable for hairy root culture because both oxygen interphase mass transfer rate and liquid flow rate were high in the whole culture process. The installation position of ultrasound transducers was optimized with the help of CFD simulation, the ultrasound transducers set at three layers around the bioreactor wall gave the highest TKE value, turbulent dissipation rate and liquid flow rate among all installation positions tested, which is positive for the dissolved oxygen mass transfer into the center of hairy root clumps. The optimized structure of the airlift sonobioreactor provided great mass transfer performance and sharply reduced the gradient of dissolved oxygen in root domain. The detection results of dissolved oxygen concentration in hairy root clumps before and after ultrasound stimulation proved that ultrasound could enhance the mass transfer of dissolved oxygen into root clumps, which is an advantage for hairy root growth and secondary metabolite accumulation. (c) 2012 The Institution of Chemical Engineers. Published by Elsevier B.V. All rights reserved. |
| WOS标题词 | Science & Technology ; Technology |
| 类目[WOS] | Engineering, Chemical |
| 研究领域[WOS] | Engineering |
| 关键词[WOS] | HAIRY-ROOT CULTURES ; BUBBLE-COLUMN REACTORS ; CELL-SUSPENSION-CULTURES ; MASS-TRANSFER BEHAVIOR ; LOW-ENERGY ULTRASOUND ; FLUID-DYNAMICS ; OXYGEN REQUIREMENTS ; ARTEMISIA-ANNUA ; SINGLE-PHASE ; BIOREACTOR |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000315614000003 |
| 公开日期 | 2015-05-27 |
| 源URL | [http://ir.ipe.ac.cn/handle/122111/13437]  |
| 专题 | 过程工程研究所_研究所（批量导入） |
| 作者单位 | Chinese Acad Sci, Inst Proc Engn, Natl Key Lab Biochem Engn, Beijing 100190, Peoples R China |
| 推荐引用方式 GB/T 7714 | Liu, Rui,Liu, Ying,Liu, Chun-Zhao. Development of an efficient CFD-simulation method to optimize the structure parameters of an airlift sonobioreactor[J]. CHEMICAL ENGINEERING RESEARCH & DESIGN,2013,91(2):211-220. |
| APA | Liu, Rui,Liu, Ying,&Liu, Chun-Zhao.(2013).Development of an efficient CFD-simulation method to optimize the structure parameters of an airlift sonobioreactor.CHEMICAL ENGINEERING RESEARCH & DESIGN,91(2),211-220. |
| MLA | Liu, Rui,et al."Development of an efficient CFD-simulation method to optimize the structure parameters of an airlift sonobioreactor".CHEMICAL ENGINEERING RESEARCH & DESIGN 91.2(2013):211-220. |
入库方式： OAI收割
来源：过程工程研究所
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