Hairy Root Culture: Bioreactor Design and Process Intensification
文献类型：期刊论文
| 作者 | Stiles, Amanda R.; Liu, Chun-Zhao; Doran, PM |
| 刊名 | BIOTECHNOLOGY OF HAIRY ROOT SYSTEMS
 |
| 出版日期 | 2013 |
| 卷号 | 134期号:0页码:91-114 |
| 关键词 | Bioreactor Computational fluid dynamics Hairy roots Process intensification |
| 英文摘要 | The cultivation of hairy roots for the production of secondary metabolites offers numerous advantages; hairy roots have a fast growth rate, are genetically stable, and are relatively simple to maintain in phytohormone free media. Hairy roots provide a continuous source of secondary metabolites, and are useful for the production of chemicals for pharmaceuticals, cosmetics, and food additives. In order for hairy roots to be utilized on a commercial scale, it is necessary to scale-up their production. Over the last several decades, significant research has been conducted on the cultivation of hairy roots in various types of bioreactor systems. In this review, we discuss the advantages and disadvantages of various bioreactor systems, the major factors related to large-scale bioreactor cultures, process intensification technologies and overview the mathematical models and computer-aided methods that have been utilized for bioreactor design and development. |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
| 类目[WOS] | Biotechnology & Applied Microbiology ; Microbiology |
| 研究领域[WOS] | Biotechnology & Applied Microbiology ; Microbiology |
| 关键词[WOS] | ARTEMISIA-ANNUA L ; NUTRIENT SPRINKLE BIOREACTOR ; TROPANE ALKALOID PRODUCTION ; BUBBLE-COLUMN REACTORS ; MASS-TRANSFER BEHAVIOR ; IN-VITRO PRODUCTION ; PLANT-CELL CULTURE ; FLUID-DYNAMICS ; HYOSCYAMUS-MUTICUS ; PANAX-GINSENG |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000331550700005 |
| 公开日期 | 2015-05-27 |
| 源URL | [http://ir.ipe.ac.cn/handle/122111/13506]  |
| 专题 | 过程工程研究所_研究所（批量导入） |
| 作者单位 | Chinese Acad Sci, Inst Proc Engn, Natl Key Lab Biochem Engn, Beijing 100190, Peoples R China |
| 推荐引用方式 GB/T 7714 | Stiles, Amanda R.,Liu, Chun-Zhao,Doran, PM. Hairy Root Culture: Bioreactor Design and Process Intensification[J]. BIOTECHNOLOGY OF HAIRY ROOT SYSTEMS,2013,134(0):91-114. |
| APA | Stiles, Amanda R.,Liu, Chun-Zhao,&Doran, PM.(2013).Hairy Root Culture: Bioreactor Design and Process Intensification.BIOTECHNOLOGY OF HAIRY ROOT SYSTEMS,134(0),91-114. |
| MLA | Stiles, Amanda R.,et al."Hairy Root Culture: Bioreactor Design and Process Intensification".BIOTECHNOLOGY OF HAIRY ROOT SYSTEMS 134.0(2013):91-114. |
入库方式： OAI收割
来源：过程工程研究所
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