The Advance of Gene Delivery Vectors
文献类型：期刊论文
| 作者 | Li Yan1,2; Yang Jun1; Liu Gui-Ying3; Zhang Xin1 |
| 刊名 | PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS
 |
| 出版日期 | 2013-10-01 |
| 卷号 | 40期号:10页码:998-1007 |
| 关键词 | gene therapy viral vectors liposomes polymers dendrimers |
| 英文摘要 | Gene therapy has rapidly emerged as a promising method for the treatment of numerous diseases. However, the intrinsic deficiencies of gene-based drugs, such as enzymatic degradation in the body, poor membrane penetrability and lack of target ability, have limited the development of its therapeutic application. Herein, it is important for efficient gene therapy to develop efficient and safe gene vectors that can deliver the gene-based drugs to targeted cells. This paper reviews the current development in gene delivery vectors, especially summarizes the characteristic and development of viral vectors, non-viral vectors and nanoparticles with tracing ability. |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
| 类目[WOS] | Biochemistry & Molecular Biology ; Biophysics |
| 研究领域[WOS] | Biochemistry & Molecular Biology ; Biophysics |
| 关键词[WOS] | POLY-L-LYSINE ; SMALL INTERFERING RNA ; MARROW STROMAL CELLS ; SIRNA DELIVERY ; IN-VIVO ; NONVIRAL VECTORS ; LIPID NANOPARTICLES ; POLYETHYLENE-GLYCOL ; CATIONIC LIPOSOMES ; SYSTEMIC DELIVERY |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000326312500013 |
| 公开日期 | 2015-05-27 |
| 源URL | [http://ir.ipe.ac.cn/handle/122111/13678]  |
| 专题 | 过程工程研究所_研究所（批量导入） |
| 作者单位 | 1.Chinese Acad Sci, Inst Proc Engn, Natl Key Lab Biochem Engn, Beijing 100190, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Capital Med Univ, Dept Pediat, Affiliated Beijing Anzhen Hosp, Beijing 100029, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li Yan,Yang Jun,Liu Gui-Ying,et al. The Advance of Gene Delivery Vectors[J]. PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS,2013,40(10):998-1007. |
| APA | Li Yan,Yang Jun,Liu Gui-Ying,&Zhang Xin.(2013).The Advance of Gene Delivery Vectors.PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS,40(10),998-1007. |
| MLA | Li Yan,et al."The Advance of Gene Delivery Vectors".PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS 40.10(2013):998-1007. |
入库方式： OAI收割
来源：过程工程研究所
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