Fabricating a Cycloolefin Polymer Immunoassay Platform with a Dual-Function Polymer Brush via a Surface-Initiated Photoiniferter-Mediated Polymerization Strategy
文献类型：期刊论文
| 作者 | Ma, Jiao ; Luan, Shifang ; Song, Lingjie ; Jin,Jing ; Yuan,Shuaishuai ; Yan,Shunjie ; Yang,Huawei ; Shi,Hengchong ; Yin,Jinghua |
| 刊名 | acs applied materials & interfaces
 |
| 出版日期 | 2014 |
| 卷号 | 6期号:3页码:1971-1978 |
| 关键词 | TRANSFER RADICAL POLYMERIZATION ANTI-FOULING SURFACES ZWITTERIONIC POLYMER COVALENT FUNCTIONALIZATION BIOLOGICAL APPLICATIONS PROTEIN ADSORPTION ACTIVE PROTEINS CELL-ADHESION BLOOD-PLASMA IMMOBILIZATION |
| 通讯作者 | luan,sf |
| 英文摘要 | the development of technologies for a biomedical detection platform is critical to meet the global challenges of various disease diagnoses. in this study, an inert cycloolefin polymer (cop) support was modified with two-layer polymer brushes possessing dual functions, i.e., a low fouling poly[poly(ethylene glycol) methacrylate] [p-(pegma)] bottom layer and a poly(acrylic acid) (paa) upper layer for antibody loading, via a surface-initiated photoiniferter-mediated polymerization strategy for fluorescence-based immunoassay. it was demonstrated through a confocal laser scanner that, for the as-prepared cop-g-peg-b-paa-igg supports, nonspecific protein adsorption was suppressed, and the resistance to nonspecific protein interference on antigen recognition was significantly improved, relative to the cop-g-paa-igg references. this strategy for surface modification of a polymeric platform is also applicable to the fabrication of other biosensors. |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000331493200083 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/52355]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Ma, Jiao,Luan, Shifang,Song, Lingjie,et al. Fabricating a Cycloolefin Polymer Immunoassay Platform with a Dual-Function Polymer Brush via a Surface-Initiated Photoiniferter-Mediated Polymerization Strategy[J]. acs applied materials & interfaces,2014,6(3):1971-1978. |
| APA | Ma, Jiao.,Luan, Shifang.,Song, Lingjie.,Jin,Jing.,Yuan,Shuaishuai.,...&Yin,Jinghua.(2014).Fabricating a Cycloolefin Polymer Immunoassay Platform with a Dual-Function Polymer Brush via a Surface-Initiated Photoiniferter-Mediated Polymerization Strategy.acs applied materials & interfaces,6(3),1971-1978. |
| MLA | Ma, Jiao,et al."Fabricating a Cycloolefin Polymer Immunoassay Platform with a Dual-Function Polymer Brush via a Surface-Initiated Photoiniferter-Mediated Polymerization Strategy".acs applied materials & interfaces 6.3(2014):1971-1978. |
入库方式： OAI收割
来源：长春应用化学研究所
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