Facile Fabrication of Single-Phase Multifunctional BaGdF5 Nanospheres as Drug Carriers
文献类型：期刊论文
| 作者 | Zhao, Qi ; Lei, Zhen ; Huang, Sa ; Han,Xueli ; Shao,Baiqi ; Lu,Wei ; Jia,Yongchao ; Lv,Wenzhen ; Jiao,Mengmeng ; Wang,Zhenxin |
| 刊名 | acs applied materials & interfaces
 |
| 出版日期 | 2014 |
| 卷号 | 6期号:15页码:12761-12770 |
| 关键词 | BIOMEDICAL APPLICATIONS MESOPOROUS SILICA CONTRAST AGENTS QUANTUM DOTS NANOPARTICLES DELIVERY CONVERSION LUMINESCENCE FLUORESCENT NANOCRYSTALS |
| 通讯作者 | wang,zx |
| 英文摘要 | multifunctional bagdf5 nanospheres with mesoporous, luminescent, and magnetic properties have been successfully synthesized with the assistance of trisodium citrate by a hydrothermal method. the mesoporous structure is revealed by scanning electron microscope and transmission electron microscope images as well as n-2 adsorption desorption isotherm. the as-synthesized bagdf5 nanospheres exhibit an intense broad bluish emission (centered at 450 nm) under the excitation of 390 nm, which might originate from the co2 center dot(-) radical-related defect produced by cit(3-) groups. it is also shown that these bagdf5 nanospheres brightened the t-1-weighted images, suggesting that they could act as t-1 contrast agents for magnetic resonance imaging. using metformin hydrochloride as the model drug, the luminescent porous spheres show good drug storage/release capability. furthermore, the emission intensity varies as a function of the cumulative drug release, making the drug-carrying system easily trackable and monitorable by detecting the luminescence intensity. additionally, the paramagnetic property, originating from the unpaired electrons of gd3+ ions, opens the possibility of directing the magnetic targeted carrier to the pathological site by magnetic field gradient. |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000340446300113 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/52370]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Zhao, Qi,Lei, Zhen,Huang, Sa,et al. Facile Fabrication of Single-Phase Multifunctional BaGdF5 Nanospheres as Drug Carriers[J]. acs applied materials & interfaces,2014,6(15):12761-12770. |
| APA | Zhao, Qi.,Lei, Zhen.,Huang, Sa.,Han,Xueli.,Shao,Baiqi.,...&Wang,Zhenxin.(2014).Facile Fabrication of Single-Phase Multifunctional BaGdF5 Nanospheres as Drug Carriers.acs applied materials & interfaces,6(15),12761-12770. |
| MLA | Zhao, Qi,et al."Facile Fabrication of Single-Phase Multifunctional BaGdF5 Nanospheres as Drug Carriers".acs applied materials & interfaces 6.15(2014):12761-12770. |
入库方式： OAI收割
来源：长春应用化学研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。