Nucleic Acid-Induced Tetraphenylethene Probe Noncovalent Self-Assembly and the Superquenching of Aggregation-Induced Emission
文献类型：期刊论文
| 作者 | Chen, Jian ; Wang, Yan ; Li, Wenying ; Zhou,Huipeng ; Li,Yongxin ; Yu,Cong |
| 刊名 | analytical chemistry
 |
| 出版日期 | 2014 |
| 卷号 | 86期号:19页码:9866-9872 |
| 关键词 | DNA METHYLTRANSFERASE ACTIVITY MONOMER-EXCIMER TRANSITION HIGHLY SENSITIVE DETECTION FREE COLORIMETRIC ASSAY ACETYLCHOLINESTERASE ACTIVITY PERYLENE PROBE CONJUGATED POLYELECTROLYTES ELECTROCHEMICAL ASSAY FLUOROMETRIC ASSAY FLUORESCENT-PROBE |
| 通讯作者 | yu,c |
| 英文摘要 | superquenching of aggregation-induced emission (aie) has been utilized in biosensing for the first time. a positively charged tetraphenylethene derivative (compound 1) showed no emission in an aqueous buffer solution. a single-stranded dna (a polyanion) induced aggregation of compound 1, and strong compound 1 aggregate emission was observed. when the dna was labeled with a quencher molecule, compound 1 aggregate emission was efficiently quenched. on the basis of this observation, a new, simple, sensitive and selective dna methyltransferase (mtase) assay has been developed. a quencher-labeled double-stranded dna could induce aggregation of compound 1, and superquenching of compound 1 aie was observed. in the presence of mtase and an endonuclease, the dna could be specifically methylated and cleaved into single-stranded dna fragments. the quencher molecule was released, and a turn-on emission signal was detected. |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000343017100075 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/52393]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Chen, Jian,Wang, Yan,Li, Wenying,et al. Nucleic Acid-Induced Tetraphenylethene Probe Noncovalent Self-Assembly and the Superquenching of Aggregation-Induced Emission[J]. analytical chemistry,2014,86(19):9866-9872. |
| APA | Chen, Jian,Wang, Yan,Li, Wenying,Zhou,Huipeng,Li,Yongxin,&Yu,Cong.(2014).Nucleic Acid-Induced Tetraphenylethene Probe Noncovalent Self-Assembly and the Superquenching of Aggregation-Induced Emission.analytical chemistry,86(19),9866-9872. |
| MLA | Chen, Jian,et al."Nucleic Acid-Induced Tetraphenylethene Probe Noncovalent Self-Assembly and the Superquenching of Aggregation-Induced Emission".analytical chemistry 86.19(2014):9866-9872. |
入库方式： OAI收割
来源：长春应用化学研究所
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