In Vitro Study of Electroactive Tetraaniline-Containing Thermosensitive Hydrogels for Cardiac Tissue Engineering
文献类型：期刊论文
| 作者 | Cui, Haitao ; Liu, Yadong ; Cheng, Yilong ; Zhang,Zhe ; Zhang,Peibiao ; Chen,Xuesi ; Wei,Yen |
| 刊名 | biomacromolecules
 |
| 出版日期 | 2014 |
| 卷号 | 15期号:4页码:1115-1123 |
| 关键词 | INJECTABLE ACELLULAR HYDROGELS EMBRYONIC STEM-CELLS ELECTRICAL-STIMULATION CARBON NANOTUBES CARDIOMYOCYTE DIFFERENTIATION MYOCARDIAL-INFARCTION ANTIOXIDANT ACTIVITY REPERFUSION INJURY REPAIR MODEL |
| 通讯作者 | chen,xs |
| 英文摘要 | injectable hydrogels made of degradable biomaterials can function as both physical support and cell scaffold in preventing infarct expansion and promoting cardiac repair in myocardial infarction therapy. here, we report in situ hydrogels consisting of thermosensitive polynipam-based copolymers and electroactive tetraaniline (ta). studies showed that the addition of 2-methylene-1,3-dioxepane (mdo) provided the polynipam-based gel with biodegradability, and the introduction of tetraaniline endowed these copolymers with desirable electrical properties and antioxidant activities. the encapsulated h9c2 cells (rat cardiac myoblast) remained highly viable in the gel matrices. in vivo gel formation and histological analyses were performed in rats by subcutaneous injection and excellent biocompatibility was observed. furthermore, the proliferation and intracellular calcium transients of h9c2 cells were also studied with (and without) electrical stimuli. both in vitro and in vivo results demonstrated that electroactive hydrogel may be used as a promising injectable biomaterial for cardiac tissue engineering. |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000334571600003 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/52396]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Cui, Haitao,Liu, Yadong,Cheng, Yilong,et al. In Vitro Study of Electroactive Tetraaniline-Containing Thermosensitive Hydrogels for Cardiac Tissue Engineering[J]. biomacromolecules,2014,15(4):1115-1123. |
| APA | Cui, Haitao.,Liu, Yadong.,Cheng, Yilong.,Zhang,Zhe.,Zhang,Peibiao.,...&Wei,Yen.(2014).In Vitro Study of Electroactive Tetraaniline-Containing Thermosensitive Hydrogels for Cardiac Tissue Engineering.biomacromolecules,15(4),1115-1123. |
| MLA | Cui, Haitao,et al."In Vitro Study of Electroactive Tetraaniline-Containing Thermosensitive Hydrogels for Cardiac Tissue Engineering".biomacromolecules 15.4(2014):1115-1123. |
入库方式： OAI收割
来源：长春应用化学研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。