In Vitro Studies on Regulation of Osteogenic Activities by Electrical Stimulus on Biodegradable Electroactive Polyelectrolyte Multilayers
文献类型：期刊论文
| 作者 | Cui, Haitao ; Wang, Yu ; Cui, Liguo ; Zhang,Peibiao ; Wang,Xianhong ; Wei,Yen ; Chen,Xuesi |
| 刊名 | biomacromolecules
 |
| 出版日期 | 2014 |
| 卷号 | 15期号:8页码:3146-3157 |
| 关键词 | PERCUTANEOUS INTRAMUSCULAR ELECTRODES MESENCHYMAL STROMAL CELLS TISSUE REGENERATION MYOBLAST DIFFERENTIATION BIOMEDICAL APPLICATIONS EXPONENTIAL-GROWTH CONDUCTING POLYMER CARBON NANOTUBES HUMAN MSCS STIMULATION |
| 通讯作者 | wei,y |
| 英文摘要 | in this study, a novel electroactive tetreaniline-containing degradable polyelectrolyte multilayer film (pem) coating [(poly(l-glutamic acid)-graft-tetreaniline/poly(l-lysine)-graft-tetreaniline)(n), (pga-g-ta/pll-g-ta)(n)] was designed and fabricated by layer-by-layer (lbl) assembly method. compared with the nongrafted pems, the tetreaniline-grafted pems showed higher roughness and stiffness in micro/nanoscale structures. the special surface characteristics and the typical electroconductive properties were more beneficial for adhesion, proliferation, and differentiation of preosteoblast mc3t3-e1 cells. moreover, the enhanced effects were observed on the modulation of mc3t3-e1 cells that differentiated into maturing osteoblasts, when the electroactive pems were coupled with electrical stimulus (es), especially in the early phase of the osteoblast differentiation. the alkaline phosphatase (alp) activity, calcium deposition, immunofluorescence staining, and rt-qpcr were evaluated on the differentiation of preosteoblast. these data indicate that the comprehensive effects through coupling electroactive scaffolds with electrical stimulus are better to develop bioelectric strategies to control cell functions for bone regeneration. |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000340348600035 |
| 源URL | [http://ir.ciac.jl.cn/handle/322003/52397]  |
| 专题 | 长春应用化学研究所_长春应用化学研究所知识产出_期刊论文 |
| 推荐引用方式 GB/T 7714 | Cui, Haitao,Wang, Yu,Cui, Liguo,et al. In Vitro Studies on Regulation of Osteogenic Activities by Electrical Stimulus on Biodegradable Electroactive Polyelectrolyte Multilayers[J]. biomacromolecules,2014,15(8):3146-3157. |
| APA | Cui, Haitao.,Wang, Yu.,Cui, Liguo.,Zhang,Peibiao.,Wang,Xianhong.,...&Chen,Xuesi.(2014).In Vitro Studies on Regulation of Osteogenic Activities by Electrical Stimulus on Biodegradable Electroactive Polyelectrolyte Multilayers.biomacromolecules,15(8),3146-3157. |
| MLA | Cui, Haitao,et al."In Vitro Studies on Regulation of Osteogenic Activities by Electrical Stimulus on Biodegradable Electroactive Polyelectrolyte Multilayers".biomacromolecules 15.8(2014):3146-3157. |
入库方式： OAI收割
来源：长春应用化学研究所
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