Protective effect of sulfated chitosan of C3 sulfation on glycerol-induced acute renal failure in rat kidney
文献类型：期刊论文
| 作者 | Xing, Ronge ; Liu, Song; Yu, Huahua; Qin, Yukun; Chen, Xiaolin; Li, Kecheng; Li, Pengcheng
|
| 刊名 | INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
 |
| 出版日期 | 2014-04-01 |
| 卷号 | 65页码:383-388 |
| 关键词 | Acute renal failure Sulfated chitosan of C3 sulfation (TCTS) Protective effect |
| 通讯作者 | Li, PC (reprint author), Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China. |
| 英文摘要 | The purpose of this study was to investigate the protective effects of sulfated chitosan of C3 sulfation (TCTS) on the glycerol-induced acute renal failure. Compared with the normal group, rats from model group exhibited collecting duct and medullary ascending limb dilation and casts by glycerol treating. TCTS, which was injected to pretreat rats by glycerol, exerted a protective effect. The results showed that serum creatinine and blood urea nitrogen were markedly increased in glycerol-treated rats. It is proved that TCTS reduced their levels significantly. Ions level in plasma and urine were significantly changed in glycerol-treated rats, whereas TCTS almost recovered their levels back to normal. For female rats, administration of TCTS reduced their mortality. This study showed a noticeable renal morphologic and functional protection by TCTS in glycerol-induced acute renal failure. Crown Copyright (C) 2014 Published by Elsevier B.V. All rights reserved. |
| 学科主题 | Biochemistry & Molecular Biology |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000334092900052 |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/24239]  |
| 专题 | 海洋研究所_海洋生物技术研发中心 海洋研究所_海洋环境工程技术研究发展中心 |
| 作者单位 | Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China |
| 推荐引用方式 GB/T 7714 | Xing, Ronge,Liu, Song,Yu, Huahua,et al. Protective effect of sulfated chitosan of C3 sulfation on glycerol-induced acute renal failure in rat kidney[J]. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,2014,65:383-388. |
| APA | Xing, Ronge.,Liu, Song.,Yu, Huahua.,Qin, Yukun.,Chen, Xiaolin.,...&Li, Pengcheng.(2014).Protective effect of sulfated chitosan of C3 sulfation on glycerol-induced acute renal failure in rat kidney.INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,65,383-388. |
| MLA | Xing, Ronge,et al."Protective effect of sulfated chitosan of C3 sulfation on glycerol-induced acute renal failure in rat kidney".INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 65(2014):383-388. |
入库方式： OAI收割
来源：海洋研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。