The transcriptomic response to copper exposure by the gill tissue of Japanese scallops (Mizuhopecten yessoensis) using deep-sequencing technology
文献类型：期刊论文
| 作者 | Meng, Xiaolin1; Tian, Xue1; Liu, Mei2; Nie, Guoxing1; Jiang, Keyong2; Wang, Baojie2; Wang, Lei2 |
| 刊名 | FISH & SHELLFISH IMMUNOLOGY
 |
| 出版日期 | 2014-06-01 |
| 卷号 | 38期号:2页码:287-293 |
| 关键词 | Mizuhopecten yessoensis Gill Copper Deep-sequencing |
| 通讯作者 | Liu, M (reprint author), Chinese Acad Sci, Inst Oceanol, R&D Ctr Marine, Qingdao 266071, Peoples R China. |
| 英文摘要 | The bivalve Mizuhopecten yessoensis has been greatly impacted by marine pollutants in northern China. To elucidate the toxicological mechanism of copper exposure on the immune system, we investigated differentially expressed genes (DEGs) and transcript abundance in M. yessoensis gill tissue using the deep-sequencing platform Illumina HiSeq (TM) 2000. In total, 1312 and 2237 genes were identified as significantly up- or down-regulated, respectively. In addition, significant enrichment analysis identified 9 GO terms and 38 pathways involved in the response to copper exposure. The analysis of immune-related transcripts revealed a complex repertoire of innate recognition receptors, including toll-like receptors, NOD-like receptors and RIG-like receptors. Downstream pathway effectors, such as apoptotic, lysosomal and C-type lectin transcripts, were also analyzed. These results will provide a resource for subsequent gene expression studies regarding heavy metal exposure and the identification of copper-sensitive biomarkers to monitor the aquaculture of M. yessoensis. (C) 2014 Elsevier Ltd. All rights reserved. |
| 学科主题 | Fisheries; Immunology; Marine & Freshwater Biology; Veterinary Sciences |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000337014700003 |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/24248]  |
| 专题 | 海洋研究所_海洋生物技术研发中心 |
| 作者单位 | 1.Henan Normal Univ, Coll Fisheries, Xinxiang 453007, Peoples R China 2.Chinese Acad Sci, Inst Oceanol, R&D Ctr Marine, Qingdao 266071, Peoples R China |
| 推荐引用方式 GB/T 7714 | Meng, Xiaolin,Tian, Xue,Liu, Mei,et al. The transcriptomic response to copper exposure by the gill tissue of Japanese scallops (Mizuhopecten yessoensis) using deep-sequencing technology[J]. FISH & SHELLFISH IMMUNOLOGY,2014,38(2):287-293. |
| APA | Meng, Xiaolin.,Tian, Xue.,Liu, Mei.,Nie, Guoxing.,Jiang, Keyong.,...&Wang, Lei.(2014).The transcriptomic response to copper exposure by the gill tissue of Japanese scallops (Mizuhopecten yessoensis) using deep-sequencing technology.FISH & SHELLFISH IMMUNOLOGY,38(2),287-293. |
| MLA | Meng, Xiaolin,et al."The transcriptomic response to copper exposure by the gill tissue of Japanese scallops (Mizuhopecten yessoensis) using deep-sequencing technology".FISH & SHELLFISH IMMUNOLOGY 38.2(2014):287-293. |
入库方式： OAI收割
来源：海洋研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。