A new ALF from Litopenaeus vannamei and its SNPs related to WSSV resistance
文献类型：期刊论文
| 作者 | Liu Jingwen1,2 ; Yu Yang1,2; Li Fuhua1,3; Zhang Xiaojun1; Xiang Jianhai1
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| 刊名 | CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY
 |
| 出版日期 | 2014-11-01 |
| 卷号 | 32期号:6页码:1232-1247 |
| 关键词 | anti-lipopolysaccharide factors (ALFs) single nucleotide polymorphisms (SNPs) white spot syndrome virus (WSSV) resistance Litopenaeus vannamei |
| 通讯作者 | Xiang, JH (reprint author), Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China. |
| 英文摘要 | Anti-lipopolysaccharide factors (ALFs) are basic components of the crustacean immune system that defend against a range of pathogens. The cDNA sequence of a new ALF, designated nLvALF2, with an open reading frame encoding 132 amino acids was cloned. Its deduced amino acid sequence contained the conserved functional domain of ALFs, the LPS binding domain (LBD). Its genomic sequence consisted of three exons and four introns. nLvALF2 was mainly expressed in the Oka organ and gills of shrimps. The transcriptional level of nLvALF2 increased significantly after white spot syndrome virus (WSSV) infection, suggesting its important roles in protecting shrimps from WSSV. Single nucleotide polymorphisms (SNPs) were found in the genomic sequence of nLvALF2, of which 38 were analyzed for associations with the susceptibility/resistance of shrimps to WSSV. The loci g. 2422 A>G, g. 2466 T>C, and g.2529 G>A were significantly associated with the resistance to WSSV (P<0.05). These SNP loci could be developed as markers for selection of WSSV-resistant varieties of Litopenaeus vannamei |
| 学科主题 | Marine & Freshwater Biology; Oceanography |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000344541900003 |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/24060]  |
| 专题 | 海洋研究所_实验海洋生物学重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Chinese Acad Sci, Inst Oceanol, Natl & Local Joint Engn Lab Ecol Mariculture, Qingdao 266071, Peoples R China |
| 推荐引用方式 GB/T 7714 | Liu Jingwen,Yu Yang,Li Fuhua,et al. A new ALF from Litopenaeus vannamei and its SNPs related to WSSV resistance[J]. CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY,2014,32(6):1232-1247. |
| APA | Liu Jingwen,Yu Yang,Li Fuhua,Zhang Xiaojun,&Xiang Jianhai.(2014).A new ALF from Litopenaeus vannamei and its SNPs related to WSSV resistance.CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY,32(6),1232-1247. |
| MLA | Liu Jingwen,et al."A new ALF from Litopenaeus vannamei and its SNPs related to WSSV resistance".CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY 32.6(2014):1232-1247. |
入库方式： OAI收割
来源：海洋研究所
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