中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Brocazines A-F, Cytotoxic Bisthiodiketopiperazine Derivatives from Penicillium brocae MA-231, an Endophytic Fungus Derived from the Marine Mangrove Plant Avicennia marina

文献类型:期刊论文

作者Meng, Ling-Hong1,2; Li, Xiao-Ming1; Lv, Cui-Ting3; Huang, Cai-Guo3; Wang, Bin-Gui1
刊名JOURNAL OF NATURAL PRODUCTS
出版日期2014-08-01
卷号77期号:8页码:1921-1927
通讯作者Huang, CG (reprint author), Second Mil Med Univ, Dept Biochem & Mol Biol, Xiangyin Rd 800, Shanghai 200433, Peoples R China.
英文摘要Six new disulfide-bridged diketopiperazine derivatives, brocazines A-F (1-6), along with one known analogue (7), were isolated and identified from the cytotoxic extract of Penicillium brocae MA-231, a fungus obtained from the fresh tissue of the marine mangrove plant Avicennia marina. The structures of these compounds were established on the basis of detailed interpretation of NMR and mass spectroscopic data. X-ray crystallographic analysis confirmed the structure of 1 and established the structure and absolute configuration of 5, while the absolute configurations for compounds 1, 4, and 6 were deduced by comparison of the CD data with those of S. Compounds 1, 2, 5, and 6 showed cytotoxic activities against several tumor cell lines.
学科主题Plant Sciences; Pharmacology & Pharmacy
收录类别SCI ; IC
语种英语
WOS记录号WOS:000340861800021
源URL[http://ir.qdio.ac.cn/handle/337002/24080]  
专题海洋研究所_实验海洋生物学重点实验室
作者单位1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
3.Second Mil Med Univ, Dept Biochem & Mol Biol, Shanghai 200433, Peoples R China
推荐引用方式
GB/T 7714
Meng, Ling-Hong,Li, Xiao-Ming,Lv, Cui-Ting,et al. Brocazines A-F, Cytotoxic Bisthiodiketopiperazine Derivatives from Penicillium brocae MA-231, an Endophytic Fungus Derived from the Marine Mangrove Plant Avicennia marina[J]. JOURNAL OF NATURAL PRODUCTS,2014,77(8):1921-1927.
APA Meng, Ling-Hong,Li, Xiao-Ming,Lv, Cui-Ting,Huang, Cai-Guo,&Wang, Bin-Gui.(2014).Brocazines A-F, Cytotoxic Bisthiodiketopiperazine Derivatives from Penicillium brocae MA-231, an Endophytic Fungus Derived from the Marine Mangrove Plant Avicennia marina.JOURNAL OF NATURAL PRODUCTS,77(8),1921-1927.
MLA Meng, Ling-Hong,et al."Brocazines A-F, Cytotoxic Bisthiodiketopiperazine Derivatives from Penicillium brocae MA-231, an Endophytic Fungus Derived from the Marine Mangrove Plant Avicennia marina".JOURNAL OF NATURAL PRODUCTS 77.8(2014):1921-1927.

入库方式: OAI收割

来源:海洋研究所

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