Anti-HIV active daphnane diterpenoids from Trigonostemon thyrsoideum
文献类型：期刊论文
| 作者 | Cheng, Yuan-Yuan1,2; Chen, Huan2,3; He, Hong-Ping1; Zhang, Yu1 ; Li, Shi-Fei1,2; Tang, Gui-Hua1,2; Guo, Ling-Li1; Yang, Wei1,2; Zhu, Feng1,2; Zheng, Yong-Tang3
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| 刊名 | PHYTOCHEMISTRY
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| 出版日期 | 2013-12-01 |
| 卷号 | 96页码:360-369 |
| 关键词 | Trigonostemon thyrsoideum Euphorbiaceae Daphnane diterpenoids Trigothysoids A-P Anti-HIV-1 |
| 英文摘要 | Sixteen daphnane diterpenoids, trigothysoids A-P, along with 15 known ones, were isolated from the methanol extract of the twigs and leaves of Trigonostemon thy rsoideum. Their structures were established by extensive spectroscopic techniques, including 2D NMR spectroscopy and mass spectrometry. The anti-HIV-1 activity of the compounds was also evaluated in vitro, and five compounds demonstrated potent anti-HIV-1 activity, with EC50 values of 0.015-0.001 nM and TI values of 1618-17,619. (C) 2013 Elsevier Ltd. All rights reserved. |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
| 类目[WOS] | Biochemistry & Molecular Biology ; Plant Sciences |
| 研究领域[WOS] | Biochemistry & Molecular Biology ; Plant Sciences |
| 关键词[WOS] | IN-VITRO ; A-G ; REIDIOIDES ; POTENT ; CHINENSIS ; TRICHOSANTHIN ; CONSTITUENTS ; INHIBITORS ; REDIOCIDE ; HOWII |
| 收录类别 | SCI ; IC |
| 语种 | 英语 |
| WOS记录号 | WOS:000328869500038 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/19233]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China 2.Chinese Acad Sci, Grad Univ, Beijing 100039, Peoples R China 3.Chinese Acad Sci, Kunming Inst Zool, Kunming 650223, Peoples R China |
| 推荐引用方式 GB/T 7714 | Cheng, Yuan-Yuan,Chen, Huan,He, Hong-Ping,et al. Anti-HIV active daphnane diterpenoids from Trigonostemon thyrsoideum[J]. PHYTOCHEMISTRY,2013,96:360-369. |
| APA | Cheng, Yuan-Yuan.,Chen, Huan.,He, Hong-Ping.,Zhang, Yu.,Li, Shi-Fei.,...&Hao, Xiao-Jiang.(2013).Anti-HIV active daphnane diterpenoids from Trigonostemon thyrsoideum.PHYTOCHEMISTRY,96,360-369. |
| MLA | Cheng, Yuan-Yuan,et al."Anti-HIV active daphnane diterpenoids from Trigonostemon thyrsoideum".PHYTOCHEMISTRY 96(2013):360-369. |
入库方式： OAI收割
来源：昆明植物研究所
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