Bioactive Polyprenylated Acylphloroglucinol Derivatives from Hypericum cohaerens
文献类型：期刊论文
| 作者 | Liu, Xia1,2; Yang, Xing-Wei1,2 ; Chen, Chao-Qun1; Wu, Chun-Yan1; Zhang, Jing-Jing1,2; Ma, Jun-Zeng1; Wang, Huan1; Yang, Li-Xin1; Xu, Gang1
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| 刊名 | JOURNAL OF NATURAL PRODUCTS
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| 出版日期 | 2013-09-01 |
| 卷号 | 76期号:9页码:1612-1618 |
| 英文摘要 | Nine new polyprenylated acylphloroglucinol derivatives, hypercohins B-J (1-9), and nine known analogues were isolated from the aerial parts of Hypericum cohaerens. The structures of 1-9 were elucidated based on spectroscopic analysis, and the absolute configuration of 1 was confirmed by X-ray crystallographic analysis. The inhibitory activities of these isolates on acetylcholinesterase and five human tumor cell lines were tested, and hypercohins B D (1-3) exhibited moderate inhibitory activity (IC50 5.8-17.9 mu M) against the tested tumor cell lines. |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
| 类目[WOS] | Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy |
| 研究领域[WOS] | Plant Sciences ; Pharmacology & Pharmacy |
| 关键词[WOS] | HENRYI SUBSP URALOIDES ; HYPERFORIN ; BENZOPHENONES |
| 收录类别 | SCI ; IC |
| 语种 | 英语 |
| WOS记录号 | WOS:000330331200014 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/19247]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100039, Peoples R China |
| 推荐引用方式 GB/T 7714 | Liu, Xia,Yang, Xing-Wei,Chen, Chao-Qun,et al. Bioactive Polyprenylated Acylphloroglucinol Derivatives from Hypericum cohaerens[J]. JOURNAL OF NATURAL PRODUCTS,2013,76(9):1612-1618. |
| APA | Liu, Xia.,Yang, Xing-Wei.,Chen, Chao-Qun.,Wu, Chun-Yan.,Zhang, Jing-Jing.,...&Xu, Gang.(2013).Bioactive Polyprenylated Acylphloroglucinol Derivatives from Hypericum cohaerens.JOURNAL OF NATURAL PRODUCTS,76(9),1612-1618. |
| MLA | Liu, Xia,et al."Bioactive Polyprenylated Acylphloroglucinol Derivatives from Hypericum cohaerens".JOURNAL OF NATURAL PRODUCTS 76.9(2013):1612-1618. |
入库方式： OAI收割
来源：昆明植物研究所
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