Melosuavines A-H, Cytotoxic Bisindole Alkaloid Derivatives from Melodinus suaveolens
文献类型：期刊论文
| 作者 | Liu, Ya-Ping1; Zhao, Yun-Li1; Feng, Tao1; Cheng, Gui-Guang1,2; Zhang, Bao-Hong3; Li, Yan1 ; Cai, Xiang-Hai1; Luo, Xiao-Dong1
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| 刊名 | JOURNAL OF NATURAL PRODUCTS
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| 出版日期 | 2013-12-01 |
| 卷号 | 76期号:12页码:2322-2329 |
| 英文摘要 | Eight new bisindole alkaloids, melosuavines A C (1-3), having an aspidosperma-scandine linkage, melosuavines D F (4-6), possessing an aspidosperma-aspidosperma skeleton, and melosuavines G and H (7 and 8) of the aspidosperma-venalatonine type, tenuicausine (9), and melodinine J (10) were isolated from the twigs and leaves of Melodinus suaveolens. The structures of 1-8 were elucidated by extensive spectroscopic methods, and compounds 9 and 10 were identified by comparison with data in the literature. The relative configuration 9 was determined from the ROESY spectrum, and some NMR signals were reassigned. Compounds 1, 2, 4-6, 8, and 10 exhibited low micromolar cytotoxicity against one or more of five human cancer cell lines. |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
| 类目[WOS] | Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy |
| 研究领域[WOS] | Plant Sciences ; Pharmacology & Pharmacy |
| 关键词[WOS] | INDOLE ALKALOIDS ; VINCA ALKALOIDS ; VINBLASTINE ; SURVIVAL ; CULTURES |
| 收录类别 | SCI ; IC |
| 语种 | 英语 |
| WOS记录号 | WOS:000329331200020 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/19248]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing, Peoples R China 3.Kunming Fengshanjian Pharmaceut Corp, Kunming, Peoples R China |
| 推荐引用方式 GB/T 7714 | Liu, Ya-Ping,Zhao, Yun-Li,Feng, Tao,et al. Melosuavines A-H, Cytotoxic Bisindole Alkaloid Derivatives from Melodinus suaveolens[J]. JOURNAL OF NATURAL PRODUCTS,2013,76(12):2322-2329. |
| APA | Liu, Ya-Ping.,Zhao, Yun-Li.,Feng, Tao.,Cheng, Gui-Guang.,Zhang, Bao-Hong.,...&Luo, Xiao-Dong.(2013).Melosuavines A-H, Cytotoxic Bisindole Alkaloid Derivatives from Melodinus suaveolens.JOURNAL OF NATURAL PRODUCTS,76(12),2322-2329. |
| MLA | Liu, Ya-Ping,et al."Melosuavines A-H, Cytotoxic Bisindole Alkaloid Derivatives from Melodinus suaveolens".JOURNAL OF NATURAL PRODUCTS 76.12(2013):2322-2329. |
入库方式： OAI收割
来源：昆明植物研究所
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