New butenolide derivatives from the marine-derived fungus Paecilomyces variotii with DPPH radical scavenging activity
文献类型：期刊论文
| 作者 | Zhang, Peng1,2 ; Li, Xiao-Ming1; Wang, Jia-Ning1,2; Li, Xin1,2; Wang, Bin-Gui1
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| 刊名 | PHYTOCHEMISTRY LETTERS
 |
| 出版日期 | 2015-03-01 |
| 卷号 | 11页码:85-88 |
| 关键词 | Marine algal-derived fungus Paecilomyces variotii Butenolide DPPH radical scavenging activity |
| 英文摘要 | Bioassay-guided fractionation of the marine-derived endophytic fungus Paecilomyces variotii resulted in the isolation of two new butenolides, namely, butyrolactone IX (1) and aspulvinone O (7), together with eight known related congeners, butyrolactones I, IV, V, and VI (2-5), aspernolide A (6), and aspulvinones H, C, and D (8-10). Their structures were elucidated on the basis of detailed spectroscopic analysis and by comparison with literature data. All of the isolated butenolides were tested for their activity against DPPH radicals and the results showed that butyrolactones (1-6) possessed potent activity with IC50 values ranging from 38.0 to 186.3 mu M, while aspulvinones (7-10) exhibited significant activities with IC50 values ranging from 11.6 to 29.4 mu M, which are stronger than that of the positive control BHT (with IC50 117.7 mu M). The preliminary structure-activity relationship was discussed. (C) 2014 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved. |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000350569100017 |
| 公开日期 | 2015-06-16 |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/25426]  |
| 专题 | 海洋研究所_实验海洋生物学重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Peng,Li, Xiao-Ming,Wang, Jia-Ning,et al. New butenolide derivatives from the marine-derived fungus Paecilomyces variotii with DPPH radical scavenging activity[J]. PHYTOCHEMISTRY LETTERS,2015,11:85-88. |
| APA | Zhang, Peng,Li, Xiao-Ming,Wang, Jia-Ning,Li, Xin,&Wang, Bin-Gui.(2015).New butenolide derivatives from the marine-derived fungus Paecilomyces variotii with DPPH radical scavenging activity.PHYTOCHEMISTRY LETTERS,11,85-88. |
| MLA | Zhang, Peng,et al."New butenolide derivatives from the marine-derived fungus Paecilomyces variotii with DPPH radical scavenging activity".PHYTOCHEMISTRY LETTERS 11(2015):85-88. |
入库方式： OAI收割
来源：海洋研究所
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