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The Role of Interoception and Insular Cortex in Addiction

文献类型：期刊论文

作者Li Chun-Lu1,2; Zhu Ning1; Li Yong-Hui1; Meng Xiao-Lu1,2; Gao Jun1,2; Sui Nan1
刊名PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS
出版日期2013
卷号40期号:1页码:15-21
关键词interoception insular cortex addiction
英文摘要Interoception is the sense of the physiological condition of the body. Recent studies suggested that interoception is involved in drug addiction and insular cortex is a key anatomical position. The neural mechanisms underlying such phenomena attract growing attention. In an effort to develop working hypotheses for future investigation, the article first reviewed the evidence of interoceptive regulation of addiction, and subsequently presented human and animal data that suggest a central role of the insular cortex in mediating interoception and addiction. On this basis, we proposed potential neurobiological mechanisms through which insular cortex may mediate drug addiction. Further, possible functional roles of neurotransmitters in the insular cortex are discussed in the context of drug addiction.
WOS标题词Science & Technology ; Life Sciences & Biomedicine
类目[WOS]Biochemistry & Molecular Biology ; Biophysics
研究领域[WOS]Biochemistry & Molecular Biology ; Biophysics
关键词[WOS]TAKING DECISION-MAKING ; FUNCTIONAL CONNECTIVITY ; NUCLEUS-ACCUMBENS ; VISCERAL CORTEX ; DRUG-ADDICTION ; RAT ; ACTIVATION ; BRAIN ; RISK ; STOP
收录类别SCI
语种英语
WOS记录号WOS:000314003100002
源URL[http://ir.psych.ac.cn/handle/311026/10804]  
专题心理研究所_中国科学院心理健康重点实验室
作者单位1.Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Beijing 100101, Peoples R China
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式
GB/T 7714		 Li Chun-Lu,Zhu Ning,Li Yong-Hui,et al. The Role of Interoception and Insular Cortex in Addiction[J]. PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS,2013,40(1):15-21.
APA Li Chun-Lu,Zhu Ning,Li Yong-Hui,Meng Xiao-Lu,Gao Jun,&Sui Nan.(2013).The Role of Interoception and Insular Cortex in Addiction.PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS,40(1),15-21.
MLA Li Chun-Lu,et al."The Role of Interoception and Insular Cortex in Addiction".PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS 40.1(2013):15-21.

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来源：心理研究所

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