Distribution of OCA2*481Thr and OCA2*615Arg, associated with hypopigmentation, in several additional populations
文献类型：期刊论文
| 作者 | Yuasa, Isao1; Harihara, Shinji2; Jin, Feng3 ; Nishimukai, Hiroaki4; Fujihara, Junko5; Fukumori, Yasuo6; Takeshita, Haruo5; Umetsu, Kazuo7; Saitou, Naruya8
|
| 刊名 | LEGAL MEDICINE
 |
| 出版日期 | 2011-07-01 |
| 卷号 | 13期号:4页码:215-217 |
| 关键词 | OCA2 Pigmentation Population-specific Population study Single nucleotide polymorphism (SNP) |
| ISSN号 | 1344-6223 |
| 产权排序 | 3 |
| 通讯作者 | Yuasa, I (reprint author), Tottori Univ, Fac Med, Div Legal Med, Yonago, Tottori 6838503, Japan. |
| 英文摘要 | Two mutants, OCA2*481Thr (c.1441G > A, p.Ala481Thr) and OCA2*615Arg (c.1844A > G, p.His615Arg), in the OCA2 (oculocutaneous albinism type II) gene are associated with hypopigmentation in East Asians. Here, these two alleles were studied to assess the frequencies in five different populations. In addition, the allele frequency of OCA2*615Arg was investigated in seven populations. Among a total of 24 global populations investigated, Oroqens in Heihe showed the highest frequency for OCA2*481Thr (0.519), and among 26 populations, Han Chinese in Changsha showed the highest frequency for OCA2*615Arg (0.673). This study confirmed that these two East Asian-specific alleles are characteristic of northern and central-southern East Asian populations. (C) 2011 Elsevier Ireland Ltd. All rights reserved. |
| 学科主题 | System biology/Biological information science |
| 收录类别 | SCI |
| 项目简介 | This study was supported in part by a Grant-in-Aid for Scientific Research (20590678 to IY) from the Japan Society for the Promotion of Science. |
| 原文出处 | http://ac.els-cdn.com/S1344622311000496/1-s2.0-S1344622311000496-main.pdf?_tid=6c550600-ada4-11e4-b951-00000aab0f6b&acdnat=1423188423_f215d18fbb0147dd5eee5c279e378db0 |
| 语种 | 英语 |
| WOS记录号 | WOS:000291776000012 |
| 源URL | [http://ir.psych.ac.cn/handle/311026/11471]  |
| 专题 | 心理研究所_中国科学院心理健康重点实验室 |
| 作者单位 | 1.Tottori Univ, Fac Med, Div Legal Med, Yonago, Tottori 6838503, Japan 2.Univ Tokyo, Grad Sch Sci, Dept Biol Sci, Tokyo 113, Japan 3.Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Beijing 100101, Peoples R China 4.Ehime Univ, Sch Med, Div Legal Med, Matsuyama, Ehime 790, Japan 5.Shimane Univ, Fac Med, Dept Legal Med, Izumo, Shimane, Japan 6.Osaka Red Cross Blood Ctr, Osaka, Japan 7.Yamagata Univ, Fac Med, Dept Forens Med, Yamagata 990, Japan 8.Natl Inst Genet, Div Populat Genet, Mishima, Shizuoka 411, Japan |
| 推荐引用方式 GB/T 7714 | Yuasa, Isao,Harihara, Shinji,Jin, Feng,et al. Distribution of OCA2*481Thr and OCA2*615Arg, associated with hypopigmentation, in several additional populations[J]. LEGAL MEDICINE,2011,13(4):215-217. |
| APA | Yuasa, Isao.,Harihara, Shinji.,Jin, Feng.,Nishimukai, Hiroaki.,Fujihara, Junko.,...&Saitou, Naruya.(2011).Distribution of OCA2*481Thr and OCA2*615Arg, associated with hypopigmentation, in several additional populations.LEGAL MEDICINE,13(4),215-217. |
| MLA | Yuasa, Isao,et al."Distribution of OCA2*481Thr and OCA2*615Arg, associated with hypopigmentation, in several additional populations".LEGAL MEDICINE 13.4(2011):215-217. |
入库方式： OAI收割
来源：心理研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。