Early prenatal morphine exposure impairs performance of learning tasks and attenuates in vitro heterosynaptic long-term potentiation of intermediate medial mesopallium in day-old chicks
文献类型：期刊论文
| 作者 | Jiang, Juan1,3 ; He, Xingu1,3; Wang, Meng-Ya2; Sui, Nan1
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| 刊名 | BEHAVIOURAL BRAIN RESEARCH
 |
| 出版日期 | 2011-06-01 |
| 卷号 | 219期号:2页码:363-366 |
| ISSN号 | 0166-4328 |
| 关键词 | Prenatal morphine exposure Passive avoidance learning (PAL) Conditioned place preference (CPP) Paired-pulse facilitation (PPF) Long-term potentiation (LTP) Intermediate medial mesopallium (IMM) |
| 通讯作者 | Sui, N (reprint author), Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Beijing 100101, Peoples R China. |
| 产权排序 | 1 |
| 英文摘要 | Based on our previous findings in day-old chicks with prenatal morphine-treated, embryonic days 5-8 is crucial for functional development of learning and memory, the underlying structure and cellular mechanisms were further explored. The prenatal morphine-exposed chicks showed deficits in passive avoidance learning and conditioned place preference, and attenuation in paired-pulse facilitation and heterosynaptic long-term potentiation in intermediate medial mesopallium (IMM) in vitro. These results suggest the altered synaptic plasticity of IMM by prenatal morphine exposure is involved in behavioral impairments. (C) 2011 Elsevier B.V. All rights reserved. |
| 学科主题 | Physiological psychology/Biological Psychology |
| 收录类别 | SCI |
| 项目简介 | This work was supported by CNBRP (2009CB522002), CNNSF (30770719), IG-CAS (KSCXI-TW-R-68) to N. Sui, AP-NSF (090413084) to M.Y. Wang and the VPSISG-CAS (2010TIS13) to Stephen Brimijoin. We also thank Y.H. Li, X.Y. Yang and B.A. Wang for their suggestions and technical assistance. |
| 语种 | 英语 |
| WOS记录号 | WOS:000289703700025 |
| 源URL | [http://ir.psych.ac.cn/handle/311026/11480]  |
| 专题 | 心理研究所_中国科学院心理健康重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Beijing 100101, Peoples R China 2.Wannan Med Coll, Cell Electrophysiol Lab, Wuhu 241002, Anhui, Peoples R China 3.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Jiang, Juan,He, Xingu,Wang, Meng-Ya,et al. Early prenatal morphine exposure impairs performance of learning tasks and attenuates in vitro heterosynaptic long-term potentiation of intermediate medial mesopallium in day-old chicks[J]. BEHAVIOURAL BRAIN RESEARCH,2011,219(2):363-366. |
| APA | Jiang, Juan,He, Xingu,Wang, Meng-Ya,&Sui, Nan.(2011).Early prenatal morphine exposure impairs performance of learning tasks and attenuates in vitro heterosynaptic long-term potentiation of intermediate medial mesopallium in day-old chicks.BEHAVIOURAL BRAIN RESEARCH,219(2),363-366. |
| MLA | Jiang, Juan,et al."Early prenatal morphine exposure impairs performance of learning tasks and attenuates in vitro heterosynaptic long-term potentiation of intermediate medial mesopallium in day-old chicks".BEHAVIOURAL BRAIN RESEARCH 219.2(2011):363-366. |
入库方式： OAI收割
来源：心理研究所
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