Exploring the metabolic network of the epidemic pathogen Burkholderia cenocepacia J2315 via genome-scale reconstruction
文献类型：期刊论文
| 作者 | Fang, Kechi2 ; Zhao, Hansheng2,3; Sun, Changyue2; Lam, Carolyn M. C.1; Chang, Suhua2,4; Zhang, Kunlin2; Panda, Gurudutta1; Godinho, Miguel1,5; dos Santos, Vitor A. P. Martins1,6; Wang, Jing2
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| 刊名 | BMC SYSTEMS BIOLOGY
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| 出版日期 | 2011-05-25 |
| 卷号 | 5 |
| ISSN号 | 1752-0509 |
| 产权排序 | 1 |
| 通讯作者 | dos Santos, VAPM (reprint author), Helmholtz Ctr Infect Res HZI, Syst & Synthet Biol Grp, Inhoffenstr 7, D-38124 Braunschweig, Germany. |
| 英文摘要 | Background: Burkholderia cenocepacia is a threatening nosocomial epidemic pathogen in patients with cystic fibrosis (CF) or a compromised immune system. Its high level of antibiotic resistance is an increasing concern in treatments against its infection. Strain B. cenocepacia J2315 is the most infectious isolate from CF patients. There is a strong demand to reconstruct a genome-scale metabolic network of B. cenocepacia J2315 to systematically analyze its metabolic capabilities and its virulence traits, and to search for potential clinical therapy targets. |
| 学科主题 | Medical psychology |
| 收录类别 | SCI |
| 项目简介 | We acknowledge funding from the European Union (Projects PROBACTYS: Grant No. 29104 and MICROME: No. 222886), the National Basic Research Program of China (973 Program) (Grant No. 2011CBA00802) from the Ministry of Science and Technology of the People's Republic of China, the Project for Young Scientists Fund, Institute of Psychology, Chinese Academy of Sciences (Grant No. O9CX115011), and Portuguese Fundacao para a Ciencia e Tecnologia (Project METAGUT; Grant No. ERA-PTG/SAU/0003/2008). |
| 原文出处 | http://www.biomedcentral.com/content/pdf/1752-0509-5-83.pdf |
| 语种 | 英语 |
| WOS记录号 | WOS:000292106500001 |
| 源URL | [http://ir.psych.ac.cn/handle/311026/11511]  |
| 专题 | 心理研究所_中国科学院心理健康重点实验室 |
| 作者单位 | 1.Helmholtz Ctr Infect Res HZI, Syst & Synthet Biol Grp, D-38124 Braunschweig, Germany 2.Chinese Acad Sci, Key Lab Mental Hlth, Inst Psychol, Beijing 100101, Peoples R China 3.China Agr Univ, Coll Biol Sci, Beijing 100193, Peoples R China 4.Chinese Acad Sci, Grad Univ, Beijing 100101, Peoples R China 5.Lifewizz Lda, P-4150616 Oporto, Portugal 6.Wageningen Univ, NL-6703 HB Wageningen, Netherlands |
| 推荐引用方式 GB/T 7714 | Fang, Kechi,Zhao, Hansheng,Sun, Changyue,et al. Exploring the metabolic network of the epidemic pathogen Burkholderia cenocepacia J2315 via genome-scale reconstruction[J]. BMC SYSTEMS BIOLOGY,2011,5. |
| APA | Fang, Kechi.,Zhao, Hansheng.,Sun, Changyue.,Lam, Carolyn M. C..,Chang, Suhua.,...&Wang, Jing.(2011).Exploring the metabolic network of the epidemic pathogen Burkholderia cenocepacia J2315 via genome-scale reconstruction.BMC SYSTEMS BIOLOGY,5. |
| MLA | Fang, Kechi,et al."Exploring the metabolic network of the epidemic pathogen Burkholderia cenocepacia J2315 via genome-scale reconstruction".BMC SYSTEMS BIOLOGY 5(2011). |
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来源：心理研究所
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