Evidence for cerebellar dysfunction in Chinese children with developmental dyslexia: an fMRI study
文献类型：期刊论文
| 作者 | Yang, Yang1,2 ; Bi, Hong-Yan1; Long, Zhi-Ying3; Tao, Sha3
|
| 刊名 | INTERNATIONAL JOURNAL OF NEUROSCIENCE
 |
| 出版日期 | 2013 |
| 卷号 | 123期号:5页码:300-310 |
| 关键词 | implicit motor learning Chinese developmental dyslexia fMRI left cerebellum |
| ISSN号 | 1365-1501 |
| 产权排序 | 1 |
| 通讯作者 | Bi, HY (reprint author), Chinese Acad Sci, Inst Psychol, Key Lab Behav Sci, Beijing 100101, Peoples R China. |
| 英文摘要 | Numerous studies reported that developmental dyslexia in alphabetic languages was associated with a wide range of sensorimotor deficits, including balance, motor skill and time estimation, explained by skill automatization deficit hypothesis. Neural correlates of skill automatization deficit point to cerebellar dysfunction. Recently, a behavioral study revealed an implicit motor learning deficit in Chinese children with developmental dyslexia in their left hands, indicating left cerebellar dysfunction. Using functional magnetic resonance imaging (fMRI), our study examined the brain activation during implicit motor learning in 9 Chinese dyslexic and 12 age-matched children. Dyslexic children showed abnormal activations in the left cerebellum, left middle/medial temporal lobe and right thalamus compared with age-matched children during implicit motor learning. These findings provide evidence of cerebellar abnormality in Chinese dyslexic people. Furthermore, dysfunction of the left cerebellum in Chinese dyslexia is inconsistent with the right cerebellum abnormalities that were reported by studies on alphabetic-language dyslexia, suggesting that neurobiological abnormalities of impaired reading are probably language specific. |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
| 学科主题 | Cognitive psychology，Developmental psychology |
| 类目[WOS] | Neurosciences |
| 研究领域[WOS] | Neurosciences & Neurology |
| 关键词[WOS] | IMPLICIT ; DEFICITS ; MOTOR ; ACTIVATION ; AWARENESS ; READERS ; LESIONS ; CORTEX ; ADULTS ; BRAIN |
| 收录类别 | SCI |
| 项目简介 | This work was supported by the National Nature Science Foundation of China (30970910, 30770726), Project for Scientists Development Fund, Institute of Psychology, Chinese Academy of Sciences (O9CX122012). |
| 语种 | 英语 |
| WOS记录号 | WOS:000317660400002 |
| 源URL | [http://ir.psych.ac.cn/handle/311026/10712]  |
| 专题 | 心理研究所_中国科学院行为科学重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Inst Psychol, Key Lab Behav Sci, Beijing 100101, Peoples R China 2.Chinese Acad Sci, Grad Univ, Beijing 100101, Peoples R China 3.Beijing Normal Univ, State Key Lab Cognit Neurosci & Learning, Beijing 100875, Peoples R China |
| 推荐引用方式 GB/T 7714 | Yang, Yang,Bi, Hong-Yan,Long, Zhi-Ying,et al. Evidence for cerebellar dysfunction in Chinese children with developmental dyslexia: an fMRI study[J]. INTERNATIONAL JOURNAL OF NEUROSCIENCE,2013,123(5):300-310. |
| APA | Yang, Yang,Bi, Hong-Yan,Long, Zhi-Ying,&Tao, Sha.(2013).Evidence for cerebellar dysfunction in Chinese children with developmental dyslexia: an fMRI study.INTERNATIONAL JOURNAL OF NEUROSCIENCE,123(5),300-310. |
| MLA | Yang, Yang,et al."Evidence for cerebellar dysfunction in Chinese children with developmental dyslexia: an fMRI study".INTERNATIONAL JOURNAL OF NEUROSCIENCE 123.5(2013):300-310. |
入库方式： OAI收割
来源：心理研究所
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