The Prognostic Value of Amplitude-Integrated EEG in Full-Term Neonates with Seizures
文献类型：期刊论文
| 作者 | Zhang, Dandan; Ding, Haiyan; Liu, Lili; Hou, Xinlin; Sun, Guoyu; Li, Lei; Liu, Yunzhe; Zhou, Congle; Gu, Ruolei ; Luo, Yuejia
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| 刊名 | PLOS ONE
 |
| 出版日期 | 2013 |
| 卷号 | 8期号:11 |
| ISSN号 | 1932-6203 |
| 产权排序 | 5 |
| 通讯作者 | Hou, XL (reprint author), Peking Univ, Hosp 1, Dept Pediat, Beijing 100871, Peoples R China. |
| 英文摘要 | Neonatal seizures pose a high risk for adverse outcome in survived infants. While the prognostic value of amplitude-integrated electroencephalogram (aEEG) is well established in neonates with encephalopathy and asphyxia, neonatal seizure studies focusing on the direct correlation between early aEEG measurement and subsequent neurologic outcome are scarce. In this study, the prognostic value of aEEG features was systematically analyzed in 143 full-term neonates to identify prognostic indicators of neurodevelopmental outcome. Neonatal aEEG features of background pattern, cyclicity, and seizure activity, as well as the etiology of neonatal seizures, were significantly associated with neurodevelopmental outcome at one year of age. aEEG background pattern was highly associated with neurologic outcomes (chi(2) = 116.9), followed by aEEG cyclicity (chi(2) = 87.2) and seizure etiology (chi(2) = 79.3). Multiple linear regression showed that the four predictors explained 71.2% of the variation in neurological outcome, with standardized beta coefficients of 0.44, 0.24, 0.22, and 0.14 for the predictors of aEEG background pattern, cyclicity, etiology, and aEEG seizure activity, respectively. This clinically applicable scoring system based on etiology and three aEEG indices would allow pediatricians to assess the risk for neurodevelopmental impairment and facilitate an early intervention in newborns developing seizures. |
| WOS标题词 | Science & Technology |
| 学科主题 | Developmental psychology ,Physiological psychology/Biological Psychology |
| 类目[WOS] | Multidisciplinary Sciences |
| 研究领域[WOS] | Science & Technology - Other Topics |
| 关键词[WOS] | HYPOXIC-ISCHEMIC ENCEPHALOPATHY ; PREDICTIVE-VALUE ; PRETERM INFANTS ; NEUROLOGIC EXAMINATION ; BIRTH ASPHYXIA ; ELECTROENCEPHALOGRAPHY ; AEEG ; HYPOTHERMIA ; NEWBORN ; BORN |
| 收录类别 | SCI |
| 项目简介 | This study was funded by the National Natural Science Foundation of China (31300867; 31300847; 91132704). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. |
| 原文出处 | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827298/pdf/pone.0078960.pdf |
| 语种 | 英语 |
| WOS记录号 | WOS:000327254700073 |
| 源URL | [http://ir.psych.ac.cn/handle/311026/10743]  |
| 专题 | 心理研究所_中国科学院行为科学重点实验室 |
| 作者单位 | Hou, XL (reprint author), Peking Univ, Hosp 1, Dept Pediat, Beijing 100871, Peoples R China. |
| 推荐引用方式 GB/T 7714 | Zhang, Dandan,Ding, Haiyan,Liu, Lili,et al. The Prognostic Value of Amplitude-Integrated EEG in Full-Term Neonates with Seizures[J]. PLOS ONE,2013,8(11). |
| APA | Zhang, Dandan.,Ding, Haiyan.,Liu, Lili.,Hou, Xinlin.,Sun, Guoyu.,...&Luo, Yuejia.(2013).The Prognostic Value of Amplitude-Integrated EEG in Full-Term Neonates with Seizures.PLOS ONE,8(11). |
| MLA | Zhang, Dandan,et al."The Prognostic Value of Amplitude-Integrated EEG in Full-Term Neonates with Seizures".PLOS ONE 8.11(2013). |
入库方式： OAI收割
来源：心理研究所
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