热门
Facial Emotion Processing in Schizophrenia: A Meta-analysis of Functional Neuroimaging Data
文献类型：期刊论文
| 作者 | Li, Huijie1,2,3 ; Chan, Raymond C. K.1,2,3,4; McAlonan, Grainne M.4,5; Gong, Qi-yong6
|
| 刊名 | SCHIZOPHRENIA BULLETIN
 |
| 出版日期 | 2010-09-01 |
| 卷号 | 36期号:5页码:1029-1039 |
| 关键词 | meta-analysis schizophrenia emotion perception amygdala |
| ISSN号 | 0586-7614 |
| 合作状况 | 国内 |
| 英文摘要 | Background: People with schizophrenia have difficulty with emotion perception. Functional imaging studies indicate regional brain activation abnormalities in patients with schizophrenia when processing facial emotion. However, findings have not been entirely consistent across different studies. Methods: Activation likelihood estimation (ALE) meta-analyses were conducted to examine brain activation during facial emotion processing in patients with schizophrenia, controls, and patients compared with controls. Secondary meta-analyses were performed to assess the contribution of task design and illness chronicity to the results reported. Results: When processing facial expressions of emotions, both patients with schizophrenia and healthy controls activated the bilateral amygdala and right fusiform gyri. However, the extent of activation in these regions was generally much more limited in the schizophrenia samples. When directly compared with controls, the extent of activation in bilateral amygdala, parahippocampal gyrus and fusiform gyrus, right superior frontal gyrus, and lentiform nucleus was significantly less in patients. Patients with schizophrenia, but not controls, activated the left insula. A relative failure to recruit the amygdala in patients occurred regardless of whether the task design was explicit or implicit, while differences in fusiform activation were evident in explicit, not implicit, tasks. Restricting the analysis to patients with chronic illness did not substantially change the results. Conclusions: A marked underrecruitment of the amygdala, accompanied by a substantial limitation in activation throughout a ventral temporal-basal ganglia-prefrontal cortex "social brain" system may be central to the difficulties patients experience when processing facial emotion. |
| 学科主题 | 认知神经科学 |
| 收录类别 | SCI ; SSCI |
| 原文出处 | http://www.ncbi.nlm.nih.gov/pubmed/19336391 |
| 语种 | 英语 |
| WOS记录号 | WOS:000281188100019 |
| 公开日期 | 2014-06-12 |
| 源URL | [http://ir.psych.ac.cn/handle/311026/10088]  |
| 专题 | 心理研究所_中国科学院心理研究所回溯数据库(1956-2010) |
| 作者单位 | 1.Chinese Acad Sci, Inst Psychol, Neuropsychol & Appl Cognit Neurosci Lab, Beijing 100101, Peoples R China 2.Chinese Acad Sci, Key Lab Mental Hlth, Beijing 100101, Peoples R China 3.Chinese Acad Sci, Grad Sch, Inst Psychol, Beijing 100101, Peoples R China 4.Univ Hong Kong, Dept Psychiat, Hong Kong, Hong Kong, Peoples R China 5.Univ Hong Kong, State Key Lab Brain & Cognit Sci, Hong Kong, Hong Kong, Peoples R China 6.Sichuan Univ, W China Sch Med, W China Hosp, Huaxi MR Res Ctr,Dept Radiol, Chengdu 610064, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, Huijie,Chan, Raymond C. K.,McAlonan, Grainne M.,et al. Facial Emotion Processing in Schizophrenia: A Meta-analysis of Functional Neuroimaging Data[J]. SCHIZOPHRENIA BULLETIN,2010,36(5):1029-1039. |
| APA | Li, Huijie,Chan, Raymond C. K.,McAlonan, Grainne M.,&Gong, Qi-yong.(2010).Facial Emotion Processing in Schizophrenia: A Meta-analysis of Functional Neuroimaging Data.SCHIZOPHRENIA BULLETIN,36(5),1029-1039. |
| MLA | Li, Huijie,et al."Facial Emotion Processing in Schizophrenia: A Meta-analysis of Functional Neuroimaging Data".SCHIZOPHRENIA BULLETIN 36.5(2010):1029-1039. |
入库方式： OAI收割
来源：心理研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。