A follow-up fMRI study of a transferable placebo anxiolytic effect
文献类型：期刊论文
| 作者 | Zhang, Wencai1 ; Qin, Shaozheng3; Guo, Jianyou1; Luo, Jing1,2; Luo, J
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| 刊名 | PSYCHOPHYSIOLOGY
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| 出版日期 | 2011-08-01 |
| 卷号 | 48期号:8页码:1119-1128 |
| 关键词 | Placebo anxiolytic effect Expectation Negative emotion Amygdala Subgenual anterior cingulate cortex Functional magnetic resonance imaging (fMRI) |
| ISSN号 | 0048-5772 |
| 产权排序 | 1 |
| 通讯作者 | Luo, J |
| 英文摘要 | Our previous study showed that placebo expectations can develop in a transferable manner; for example, a placebo expectation developed within an analgesic experience may lead to reduced anxiety. Considering that activities in such emotion-responsive areas as the amygdala and insula can be detected through functional magnetic resonance imaging (fMRI), we used fMRI to further study the transferable placebo anxiolytic effect. A main-effect analysis showed that activity in the amygdala and insula was reduced in the placebo condition, whereas an interaction analysis showed activity in the two regions was selectively attenuated in the placebo condition when unpleasant pictures were viewed. We also observed greater activity in the subgenual anterior cingulate cortex under placebo conditions when either emotionally negative or neutral pictures were viewed. These data suggest that the anxiety-relieving placebo effect arose from a reward-related response underpinned by the participants' expectations. |
| 学科主题 | 健康心理学 |
| 收录类别 | SCI ; SSCI |
| 项目简介 | This research was supported by the National Basic Research Program of China (Grant 2010CB833904), the National Natural Science Foundation of China (Grants 30970890 and 30770708), the National Hi-Tech Research and Development Program of China (Grants 2008AA022604 and 2009BAI77B06), the Young Scientists Fund of the Institute of Psychology (Grant Y0CX451S01), and the Knowledge Innovation Program of the Chinese Academy of Sciences (Grant KSCX2-EW-J-8). |
| 原文出处 | http://onlinelibrary.wiley.com/doi/10.1111/j.1469-8986.2011.01178.x/pdf |
| 语种 | 英语 |
| WOS记录号 | WOS:000292449900010 |
| 源URL | [http://ir.psych.ac.cn/handle/311026/10851]  |
| 专题 | 心理研究所_中国科学院心理健康重点实验室 |
| 通讯作者 | Luo, J |
| 作者单位 | 1.Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Beijing 100101, Peoples R China 2.Capital Normal Univ, Learning & Cognit Lab, Beijing, Peoples R China 3.Radboud Univ Nijmegen, Donders Inst Brain Cognit & Behav, Ctr Cognit Neuroimaging, NL-6525 ED Nijmegen, Netherlands |
| 推荐引用方式 GB/T 7714 | Zhang, Wencai,Qin, Shaozheng,Guo, Jianyou,et al. A follow-up fMRI study of a transferable placebo anxiolytic effect[J]. PSYCHOPHYSIOLOGY,2011,48(8):1119-1128. |
| APA | Zhang, Wencai,Qin, Shaozheng,Guo, Jianyou,Luo, Jing,&Luo, J.(2011).A follow-up fMRI study of a transferable placebo anxiolytic effect.PSYCHOPHYSIOLOGY,48(8),1119-1128. |
| MLA | Zhang, Wencai,et al."A follow-up fMRI study of a transferable placebo anxiolytic effect".PSYCHOPHYSIOLOGY 48.8(2011):1119-1128. |
入库方式： OAI收割
来源：心理研究所
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