The catalytic reforming of CH4 with CO2 has received extensive attention of industrial and academic circles all over the world. This reaction has also important environmental implications because both CH4 and CO2 are regarded as the main factors leading to the green-house effect. Thus, this process exhibits certain poten- tial to be used as thermochemical heat-pipe for recovery, storage and transmission of solar and other renewable energy sources. At present, one of the key problems for the application of this process is the development of practical catalysts with high activity and high stability. But the catalyst for the reaction at home and abroad studies have been largely focused on precious metals and nickel-based catalysts, precious metal catalyst is expensive , carbon deposition of nickel-based catalysts at the same time is serious and has low stability. The work is focused on the study of Ni-based catalysts, which has aeries of excellent catalytic activity and unique resistance of Ni catalysts by rational design. In this paper, the modified Ni-based catalysts have been prepared with piallared vermiculite as supports, which Ni contents weer between 4-12swt% and different metals as promoter, and characterized by XRD, BET, TGA, TPR, SEM, XPS and TEM. The catalytic performance and deactivation mechanism of catalysts have been investigated in the simultaneous oxidative conversion and CO2 reforming of methane to syngas. The natural vermiculite supplied from Weilim iner of Xinjiangwas submitted to an nitric acid treatment followed by calcinations, oxalic acid treatment, and sodium form by ion exchange, which results in the increase of the framework Al ratio, the reduction of the layer charge density, and the conversion of the vermiculite into a form of sodium- vermiculite. The results showed that the nitric acid concentrations 3mol/L and [OH-]:Al3+=2.4。 The Ni/CPVMT catalyst with Ni loading of 12wt% exhibited the highest catalytic activity. The catalytic activity and stability of Ni/CPVMT catalyst increased with calcined temperature increasing due to the stronger interaction between nickel particles and the support. The addition of Mg, Ca, La and Ba into Ni/CPVMT effectively enhanced the catalytic activity and stability of catalysts. The alkaline earth metal-modified Ni catalysts exhibited better catalytic activity and stability than alkali metal-modified ones. The addition of different metals as promoter improved metal-support interaction to some degree. The addition of Ca into Ni/CPVMT promoted the dispersion of Ni and prevented the sintering .