New vobasinyl-ibogan type bisindole alkaloids from Tabernaemontana corymbosa
文献类型：期刊论文
| 作者 | Zhang, Yu ; Guo, Lingli; Yang, Guangmei; Guo, Feng; Di, Yingtong; Li, Shunlin; Chen, Duozhi; Hao, Xiaojiang
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| 刊名 | FITOTERAPIA
 |
| 出版日期 | 2015 |
| 卷号 | 100页码:150-155 |
| 关键词 | Tabernaemontana corymbosa Bisindole alkaloids Tabercorines A-C Cytotoxicity |
| 英文摘要 | Ten vobasinyl-ibogan type bisindole alkaloids, including three new ones, tabercorines A-C (1-3), and a new natural product, 17-acetyl-tabemaecorymbosine A (4), were isolated from the twigs and leaves of Tabernaemontana coymbosa. Their structures were elucidated on the basis of spectroscopic data, and the NMR data of 17-acetyl-tabemaecorymbosine A (4) was assigned and reported for the first time. The absolute configurations of 1-4 were determined by CD exciton chirality method. All new compounds were evaluated for in vitro cytotoxicity against various human cancer cell lines. Compounds 1 and 4 showed significant inhibitory effects with IC50 values comparable to those of cisplatin. (C) 2014 Elsevier B.V. All rights reserved. |
| 类目[WOS] | Chemistry, Medicinal ; Pharmacology & Pharmacy |
| 研究领域[WOS] | Pharmacology & Pharmacy |
| 关键词[WOS] | INDOLE ALKALOIDS ; ERVATAMIA-CHINENSIS |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000349881300019 |
| 公开日期 | 2015-07-07 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/20431]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Yu,Guo, Lingli,Yang, Guangmei,et al. New vobasinyl-ibogan type bisindole alkaloids from Tabernaemontana corymbosa[J]. FITOTERAPIA,2015,100:150-155. |
| APA | Zhang, Yu.,Guo, Lingli.,Yang, Guangmei.,Guo, Feng.,Di, Yingtong.,...&Hao, Xiaojiang.(2015).New vobasinyl-ibogan type bisindole alkaloids from Tabernaemontana corymbosa.FITOTERAPIA,100,150-155. |
| MLA | Zhang, Yu,et al."New vobasinyl-ibogan type bisindole alkaloids from Tabernaemontana corymbosa".FITOTERAPIA 100(2015):150-155. |
入库方式： OAI收割
来源：昆明植物研究所
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