Three new 11,20-epoxy-ent-kauranoids from Isodon rubescens
文献类型：期刊论文
| 作者 | Liu, Xu1; Zhan, Rui2; Wang, Wei Guang2; Du, Xue2; Li, Yan2 ; Zhang, Peng1; Pu, Jian Xin2; Wu, Ji Zhou1; Sun, Han Dong2
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| 刊名 | ARCHIVES OF PHARMACAL RESEARCH
 |
| 出版日期 | 2012-12-01 |
| 卷号 | 35期号:12页码:2147-2151 |
| 关键词 | Jianshirubesins D-F 11 Isodon rubescens Cytotoxicity 20-Epoxy-ent-kauranoids |
| 英文摘要 | Three rare and new 11,20-epoxy-ent-kaurane diterpenoids, named jianshirubesins D-F (1-3), along with one known analogue (4), were isolated from the aerial parts of Isodon rubescens. Their structures were established by analysis of spectroscopic data. Found in the MTT assay to evaluate the cytotoxicity of compounds 1, 2, and 4, only 1 could selectively inhibit certain cell lines from proliferating. In addition, a simple structure-activity relationship discussion might suggest a new bioactive moiety, different from the alpha,beta-unsaturated ketone group. |
| 类目[WOS] | Chemistry, Medicinal ; Pharmacology & Pharmacy |
| 研究领域[WOS] | Pharmacology & Pharmacy |
| 关键词[WOS] | ABIETANE DITERPENOIDS ; VAR.-LUSHIENSIS ; CYTOTOXICITY ; CONSTITUENTS |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000312772900012 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/20443]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Huazhong Univ Sci & Technol, Hubei Key Lab Nat Med Chem & Resource Evaluat, Tongji Sch Pharm, Wuhan 430030, Hubei, Peoples R China 2.Chinese Acad Sci, State Key Lab Phytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Yunnan, Peoples R China |
| 推荐引用方式 GB/T 7714 | Liu, Xu,Zhan, Rui,Wang, Wei Guang,et al. Three new 11,20-epoxy-ent-kauranoids from Isodon rubescens[J]. ARCHIVES OF PHARMACAL RESEARCH,2012,35(12):2147-2151. |
| APA | Liu, Xu.,Zhan, Rui.,Wang, Wei Guang.,Du, Xue.,Li, Yan.,...&Sun, Han Dong.(2012).Three new 11,20-epoxy-ent-kauranoids from Isodon rubescens.ARCHIVES OF PHARMACAL RESEARCH,35(12),2147-2151. |
| MLA | Liu, Xu,et al."Three new 11,20-epoxy-ent-kauranoids from Isodon rubescens".ARCHIVES OF PHARMACAL RESEARCH 35.12(2012):2147-2151. |
入库方式： OAI收割
来源：昆明植物研究所
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