Cytotoxic 9,19-cycloartane triterpenes from the aerial parts of Cimicifuga yunnanensis
文献类型：期刊论文
| 作者 | Bao, Ni-Man1,2; Nian, Yin1 ; Zhu, Guo-Lei1; Wang, Wei-Hua1; Zhou, Lin1; Qiu, Ming-Hua1,2
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| 刊名 | FITOTERAPIA
 |
| 出版日期 | 2014-12-01 |
| 卷号 | 99页码:191-197 |
| 关键词 | 18(13 -> 12)Abeo-9 Cimicifuga yunnanensis Cytotoxicity 19-cycloartane triterpenes |
| 英文摘要 | Six new 9,19-cycloartane triterpenes (1-6) were isolated from the aerial parts of Cimicifuga yunnanensis. The new chemical structures were determined by extensive analyses of 1D and 2D NMR spectroscopy. Compounds 1 and 2 are the first 9,19-cycloartane triterpenes characterized by CH3-18 shifting from C-13 to C-12 in the Cimicifuga spp. The evaluation of inhibition activity against human HL-60, SMMC-7721, A-549, MCF-7, and SW480 cell lines indicated that compounds 1-6 showed different levels of cytotoxic activities with IC50 values ranging from 1.2 to 27.8 mu m. (C) 2014 Elsevier B.V. All rights reserved. |
| 类目[WOS] | Chemistry, Medicinal ; Pharmacology & Pharmacy |
| 研究领域[WOS] | Pharmacology & Pharmacy |
| 关键词[WOS] | PROLIFERATION ; CONSTITUENTS ; APOPTOSIS ; RACEMOSA ; CELLS ; ASSAY |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000347019000024 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/20468]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China 2.Yunnan Univ, Sch Chem Sci & Technol, Minist Educ, Kunming 650091, Yunnan, Peoples R China |
| 推荐引用方式 GB/T 7714 | Bao, Ni-Man,Nian, Yin,Zhu, Guo-Lei,et al. Cytotoxic 9,19-cycloartane triterpenes from the aerial parts of Cimicifuga yunnanensis[J]. FITOTERAPIA,2014,99:191-197. |
| APA | Bao, Ni-Man,Nian, Yin,Zhu, Guo-Lei,Wang, Wei-Hua,Zhou, Lin,&Qiu, Ming-Hua.(2014).Cytotoxic 9,19-cycloartane triterpenes from the aerial parts of Cimicifuga yunnanensis.FITOTERAPIA,99,191-197. |
| MLA | Bao, Ni-Man,et al."Cytotoxic 9,19-cycloartane triterpenes from the aerial parts of Cimicifuga yunnanensis".FITOTERAPIA 99(2014):191-197. |
入库方式： OAI收割
来源：昆明植物研究所
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