Geissoschizine methyl ether N- oxide, a new alkaloid with antiacetylcholinesterase activity from Uncaria rhynchophylla
文献类型：期刊论文
| 作者 | Jiang, Wei-Wei; Su, Jia; Wu, Xing-De; He, Juan; Peng, Li-Yan; Cheng, Xiao; Zhao, Qin-Shi
|
| 刊名 | NATURAL PRODUCT RESEARCH
 |
| 出版日期 | 2015-05-03 |
| 卷号 | 29期号:9页码:842-847 |
| 关键词 | Uncaria rhynchophylla Rubiaceae alkaloids geissoschizine methyl ether N-oxide anti-AChE activity |
| 通讯作者 | Zhao,QS (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650204,Peoples R China. ; qinshizhao@mail.kib.ac.cn |
| 英文摘要 | Geissoschizine methyl ether N-oxide, a new oxindole alkaloid, along with 14 known alkaloids, was isolated from the aerial part of Uncaria rhynchophylla. Their structures were identified by comprehensive spectral methods, including 2D NMR experiments, and confirmed by comparing with the literature data. In vitro acetylcholinesterase (AChE) inhibitory activity assay showed that the new compound exhibited anti-AChE activity with IC50 value of 23.4M. |
| 学科主题 | Chemistry, Applied; Chemistry, Medicinal |
| 类目[WOS] | Chemistry, Applied ; Chemistry, Medicinal |
| 研究领域[WOS] | Chemistry ; Pharmacology & Pharmacy |
| 关键词[WOS] | INDOLE ALKALOIDS ; LEAVES ; PLANTS |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000352853400010 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/20586]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Jiang, Wei-Wei,Su, Jia,Wu, Xing-De,et al. Geissoschizine methyl ether N- oxide, a new alkaloid with antiacetylcholinesterase activity from Uncaria rhynchophylla[J]. NATURAL PRODUCT RESEARCH,2015,29(9):842-847. |
| APA | Jiang, Wei-Wei.,Su, Jia.,Wu, Xing-De.,He, Juan.,Peng, Li-Yan.,...&Zhao, Qin-Shi.(2015).Geissoschizine methyl ether N- oxide, a new alkaloid with antiacetylcholinesterase activity from Uncaria rhynchophylla.NATURAL PRODUCT RESEARCH,29(9),842-847. |
| MLA | Jiang, Wei-Wei,et al."Geissoschizine methyl ether N- oxide, a new alkaloid with antiacetylcholinesterase activity from Uncaria rhynchophylla".NATURAL PRODUCT RESEARCH 29.9(2015):842-847. |
入库方式： OAI收割
来源：昆明植物研究所
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