Hypersubones A and B, New Polycyclic Acylphloroglucinols with Intriguing Adamantane Type Cores from Hypericum subsessile
文献类型：期刊论文
| 作者 | Liao, Yang1,2; Liu, Xia1; Yang, Jing1; Lao, Yuan-Zhi3; Yang, Xing-Wei1,2 ; Li, Xiao-Nian1; Zhang, Jing-Jing1; Ding, Zhi-jie3; Xu, Hong-Xi3; Xu, Gang1
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| 刊名 | ORGANIC LETTERS
 |
| 出版日期 | 2015-03-06 |
| 卷号 | 17期号:5页码:1172-1175 |
| 通讯作者 | Xu,HX (reprint author),Shanghai Univ Tradit Chinese Med,Sch Pharm,Shanghai 201203,Peoples R China. ; xuhongxi88@gmail.com ; xugang008@mail.kib.ac.cn |
| 英文摘要 | Hypersubones A and B (1, 2), two adamantane type polycyclic polyprenylated acylphloroglucinols possessing an unprecedented seco-adamantane architecture and a tetracyclo-[6.3.1.13,10.04,8]-tridecane core combined with a peroxide ring, respectively, were isolated from Hypericum subsessile together with three analogues (3-5). Their structures were determined by extensive NMR spectroscopic analysis, ECD calculations, and single-crystal X-ray diffraction. Compound 2 exhibited significant cytotoxicities against four human cancer lines in vitro (IC50 0.07-7.52 mu M). |
| 学科主题 | Chemistry, Organic |
| 类目[WOS] | Chemistry, Organic |
| 研究领域[WOS] | Chemistry |
| 关键词[WOS] | POLYPRENYLATED ACYLPHLOROGLUCINOLS ; MEDICINAL CHEMISTRY ; DERIVATIVES ; SAMPSONII ; GUTTIFERAE ; ANNULATION ; SKELETON |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000350841300029 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/20590]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Shanghai Univ Tradit Chinese Med, Sch Pharm, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Liao, Yang,Liu, Xia,Yang, Jing,et al. Hypersubones A and B, New Polycyclic Acylphloroglucinols with Intriguing Adamantane Type Cores from Hypericum subsessile[J]. ORGANIC LETTERS,2015,17(5):1172-1175. |
| APA | Liao, Yang.,Liu, Xia.,Yang, Jing.,Lao, Yuan-Zhi.,Yang, Xing-Wei.,...&Xu, Gang.(2015).Hypersubones A and B, New Polycyclic Acylphloroglucinols with Intriguing Adamantane Type Cores from Hypericum subsessile.ORGANIC LETTERS,17(5),1172-1175. |
| MLA | Liao, Yang,et al."Hypersubones A and B, New Polycyclic Acylphloroglucinols with Intriguing Adamantane Type Cores from Hypericum subsessile".ORGANIC LETTERS 17.5(2015):1172-1175. |
入库方式： OAI收割
来源：昆明植物研究所
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