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New clerodane diterpenoids from the twigs and leaves of Croton euryphyllus

文献类型：期刊论文

作者Pan, Zhenghong1; Ning, Desheng1; Wu, Xingde2; Huang, Sisi1; Li, Dianpeng1; Lv, Shihong1
刊名BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
出版日期2015-03-15
卷号25期号:6页码:1329-1332
关键词Croton euryphyllus Crotoeurins A-C Nor-clerodane diterpenoid Neurite outgrowth-promoting activity
通讯作者Pan,ZH (reprint author),Chinese Acad Sci,Guangxi Inst Bot,Guangxi Key Lab Funct Phytochem Res & Utilizat,Guilin 541006,Peoples R China. ; pan7260@126.com
英文摘要Three new nor-clerodane diterpenoids, crotoeurins A-C (1-3), together with four known ones were isolated from the twigs and leaves of Croton euryphyllus. Among them, crotoeurin A (1) is a new nor-clerodane diterpenoid dimer with a unique cyclobutane ring via a [2+2] cycloaddition. Their structures were elucidated by spectroscopic analyses and the stereochemistry of 1 was confirmed by single-crystal X-ray diffraction analysis. Compounds 1-3 exhibited neurite outgrowth-promoting activity on NGF-mediated PC12 cells at concentration of 10 mu M. (C) 2015 Elsevier Ltd. All rights reserved.
学科主题Chemistry, Medicinal; Chemistry, Organic
类目[WOS]Chemistry, Medicinal ; Chemistry, Organic
研究领域[WOS]Pharmacology & Pharmacy ; Chemistry
关键词[WOS]NGF-POTENTIATING ACTIVITY ; NEOCLERODANE DITERPENOIDS
收录类别SCI
语种英语
WOS记录号WOS:000350696000032
源URL[http://ir.kib.ac.cn/handle/151853/20601]  
专题昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
作者单位1.Chinese Acad Sci, Guangxi Inst Bot, Guangxi Key Lab Funct Phytochem Res & Utilizat, Guilin 541006, Peoples R China
2.Chinese Acad Sci, Kunming Inst Bot, Kunming 650204, Peoples R China
推荐引用方式
GB/T 7714		 Pan, Zhenghong,Ning, Desheng,Wu, Xingde,et al. New clerodane diterpenoids from the twigs and leaves of Croton euryphyllus[J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS,2015,25(6):1329-1332.
APA Pan, Zhenghong,Ning, Desheng,Wu, Xingde,Huang, Sisi,Li, Dianpeng,&Lv, Shihong.(2015).New clerodane diterpenoids from the twigs and leaves of Croton euryphyllus.BIOORGANIC & MEDICINAL CHEMISTRY LETTERS,25(6),1329-1332.
MLA Pan, Zhenghong,et al."New clerodane diterpenoids from the twigs and leaves of Croton euryphyllus".BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 25.6(2015):1329-1332.

入库方式： OAI收割

来源：昆明植物研究所

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