Sweriyunnanlactone A, one unusual secoiridoid trimer from Swertia yunnanensis
文献类型：期刊论文
| 作者 | Geng, Chang-An ; Chen, Xing-Long; Huang, Xiao-Yan; Ma, Yun-Bao; He, Kang; Zhou, Ning-Jia; Cao, Tuan-Wu; Zhang, Xue-Mei; Chen, Ji-Jun
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| 刊名 | TETRAHEDRON LETTERS
 |
| 出版日期 | 2015-04-22 |
| 卷号 | 56期号:17页码:2163-2166 |
| 关键词 | Sweriyunnanlactone A Secoiridoid trimer Swertia yunnanensis LC-MS guided isolation Anti-HBV activity |
| 英文摘要 | One unusual secoiridoid trimer, namely sweriyunnanlactone A (1), was isolated from Swertia yunnanensis under the guidance of LC-MS analysis. Sweriyunnanlactone A with a phenyl ring (ring F) was the first example of secoiridoid trimer featuring a C-28 skeleton. Its structure was determined by extensive HRESIMS, 1D and 2D NMR spectroscopic data, and GIAO C-13 NMR calculation. Compound 1 showed weak inhibition on HBV DNA replication with an IC50 value of 60.76 mu M (SI = 12.6) on HepG 2.2.15 cell line in vitro. (C) 2015 Elsevier Ltd. All rights reserved. |
| 类目[WOS] | Chemistry, Organic |
| 研究领域[WOS] | Chemistry |
| 关键词[WOS] | B VIRUS ACTIVITY ; CHEMICAL-CONSTITUENTS ; MILEENSIS ; LACTONES ; EXAMPLE |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000353745900008 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/20689]  |
| 专题 | 昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China |
| 推荐引用方式 GB/T 7714 | Geng, Chang-An,Chen, Xing-Long,Huang, Xiao-Yan,et al. Sweriyunnanlactone A, one unusual secoiridoid trimer from Swertia yunnanensis[J]. TETRAHEDRON LETTERS,2015,56(17):2163-2166. |
| APA | Geng, Chang-An.,Chen, Xing-Long.,Huang, Xiao-Yan.,Ma, Yun-Bao.,He, Kang.,...&Chen, Ji-Jun.(2015).Sweriyunnanlactone A, one unusual secoiridoid trimer from Swertia yunnanensis.TETRAHEDRON LETTERS,56(17),2163-2166. |
| MLA | Geng, Chang-An,et al."Sweriyunnanlactone A, one unusual secoiridoid trimer from Swertia yunnanensis".TETRAHEDRON LETTERS 56.17(2015):2163-2166. |
入库方式： OAI收割
来源：昆明植物研究所
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