中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Synthesis and Antifungal Activities of New Type beta-Methoxyacrylate-Based Strobilurin Analogues

文献类型:期刊论文

作者Zhang Xiang ; Liu Huijun ; Gao Yongxin ; Wang Huili ; Guo Baoyuan ; Li Jianzhong
刊名CHINESE JOURNAL OF CHEMISTRY
出版日期2012
卷号30期号:7页码:1517-1524
关键词synthesis strobilurin derivatives antifungal activities substituted pyrimidine SAR
ISSN号1001-604X
中文摘要Strobilurins have become one of the most important classes of agricultural fungicides. To discover new strobilurin derivatives with high activity against resistant pathogens, a series of novel beta-methoxyacrylate analogues were designed and synthesized by integrating substituted pyrimidine with a strobilurin pharmacophore. The compounds were confirmed and characterized by infrared, 1H nuclear magnetic resonance, elemental analysis and mass spectroscopy. The bioassays indicated that most of the compounds 1 exhibited potent antifungal activity against Colletotrichum orbiculare, Botrytis cinerea Pers and Phytophthora capsici Leonian at the concentration of 50 mu g/mL. Exhilaratingly, compound 1a (R=methyl) showed better antifungal activity against all the tested fungi than the commercial strobilurin fungicide azoxystrobin.
WOS记录号WOS:000306562300025
公开日期2014-11-05
源URL[http://ir.rcees.ac.cn/handle/311016/7922]  
专题生态环境研究中心_中国科学院环境生物技术重点实验室
推荐引用方式
GB/T 7714
Zhang Xiang,Liu Huijun,Gao Yongxin,et al. Synthesis and Antifungal Activities of New Type beta-Methoxyacrylate-Based Strobilurin Analogues[J]. CHINESE JOURNAL OF CHEMISTRY,2012,30(7):1517-1524.
APA Zhang Xiang,Liu Huijun,Gao Yongxin,Wang Huili,Guo Baoyuan,&Li Jianzhong.(2012).Synthesis and Antifungal Activities of New Type beta-Methoxyacrylate-Based Strobilurin Analogues.CHINESE JOURNAL OF CHEMISTRY,30(7),1517-1524.
MLA Zhang Xiang,et al."Synthesis and Antifungal Activities of New Type beta-Methoxyacrylate-Based Strobilurin Analogues".CHINESE JOURNAL OF CHEMISTRY 30.7(2012):1517-1524.

入库方式: OAI收割

来源:生态环境研究中心

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